ArticleHeart (British Cardiac Society)2017
Survival adjusted cancer risks attributable to radiation exposure from cardiac catheterisations in children.
Article in Heart (British Cardiac Society), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of spinal angiography in the evaluation and treatment of pediatric spinal vascular pathology: a case series and systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Pooled it
- Radiation Reduction Through the Use of a Novel Ultra-Low Dose Fluoroscopy Imaging Protocol in Congenital Cardiac Catheterization.Pediatric cardiology · 2026Article
- Decreasing radiation exposure in interventional pediatric cardiology: a 10-year European single-center analysis of 3683 procedures.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Radiation Exposure during Cardiac Interventions in Congenital Heart Defects: A Multicenter German Registry Analysis 2012-2020.The Thoracic and cardiovascular surgeon · 2025Article
- Real-time automatic image-based slice tracking of gadolinium-filled balloon wedge catheter during MR-guided cardiac catheterization: A proof-of-concept study.Magnetic resonance in medicine · 2024Article
- A new classification of cardio-oncology syndromes.Cardio-oncology (London, England) · 2021Review
- Radiation Exposure in Pediatric Interventional Procedures.Cardiovascular and interventional radiology · 2021Review
- MRI for Guided Right and Left Heart Cardiac Catheterization: A Prospective Study in Congenital Heart Disease.Journal of magnetic resonance imaging : JMRI · 2021Article
- Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).European journal of heart failure · 2020Article
- Catheter strategy to ease the procedure and reduce radiation exposure when requiring neck access.Open heart · 2020Article
- Age-specific and gender-specific radiation risks in paediatric angiography and interventional cardiology: conversion coefficients and risk reference values.The British journal of radiology · 2020Article
- Increased Cancer Incidence Following up to 15 Years after Cardiac Catheterization in Infants under One Year between 1980 and 1998-A Single Center Observational Study.Journal of clinical medicine · 2020Article
- Transcatheter and intraoperative device closure of atrial septal defect in infants under three years of age.Journal of cardiothoracic surgery · 2020Article
- Cancer incidence after childhood irradiation for tinea capitis in a Portuguese cohort.The British journal of radiology · 2020Article
- Risk of Cancer Among Children and Young Adults With Congenital Heart Disease Compared With Healthy Controls.JAMA network open · 2019Article
- Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019Article
- Transcatheter Atrial Septal Defect Closure in Children with and without Fluoroscopy: A Comparison.Journal of interventional cardiology · 2019Observational
- Catheter, MRI and CT Imaging in Newborns with Pulmonary Atresia with Ventricular Septal Defect and Aortopulmonary Collaterals: Quantifying the Risks of Radiation Dose and Anaesthetic Time.Pediatric cardiology · 2018Article
- Assessment of PCXMC for patients with different body size in chest and abdominal x ray examinations: a Monte Carlo simulation study.Physics in medicine and biology · 2018Article
- Projected cancer risks potentially related to past, current, and future practices in paediatric CT in the United Kingdom, 1990-2020.British journal of cancer · 2017Article
Corrections and comments
- Commented on by
Authors and funding
6 authors.
Funding
Abstract
objectivesTo estimate the risk of developing cancer in relation to the typical radiation doses received from a range of X-ray guided cardiac catheterisations in children, taking variable survival into account.
methodsRadiation doses were estimated for 2749 procedures undertaken at five UK hospitals using Monte Carlo simulations. The lifetime attributable risk (LAR) of cancer incidence was estimated using models developed by the Biological Effects of Ionising Radiation committee, based on both normal life expectancy, and as a function of attained age, from 20 to 80 years, to take reduced life expectancy into account.
resultsThe radiation-related risks from these procedures are dominated by lung and breast cancer (for females). Assuming normal life expectancy, central LAR estimates for cancer incidence, based on median doses, ranged from <1 in 2000 for atrial septal defect occlusions to as high as 1 in 150 for valve replacements. For a reduced life expectancy of 50 years, estimated risks are lower by a factor of around 7. For conditions with especially poor survival (age 20 years), such as hypoplastic left heart syndrome, estimated cancer risks attributable to radiation were <1 in 20 000.
conclusionsBased on recent UK radiation dose levels, the risk of cancer following cardiac catheterisations is relatively low and strongly modified by survival and the type of procedure. The risk of breast cancer, especially following pulmonary artery angioplasty and valve replacements, is the greatest concern.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.