Evidence map›Paper›PMID 27540173›Full record

ArticleScience (New York, N.Y.)2016

Integration of omic networks in a developmental atlas of maize.

Justin W Walley, Ryan C Sartor, Zhouxin Shen, Robert J Schmitz, Kevin J Wu, Mark A Urich, Joseph R Nery, Laurie G Smith, James C Schnable, Joseph R Ecker and 1 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 256 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
256citing papers in PubMed, 1 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

256 citing papers in PubMed, 1 synthesis or guideline pooled it, 531 citations in OpenAlex.

  1. Pooled it
  2. Genetic determinants of aerial root morphology in Sierra Mixe-derived maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Maize Anther Development Involves Translated Open Reading Frames From 3' Untranslated Regions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Review
  8. Article
  9. Identification ofPlants (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. CRISPR/Cas9-MediatedPlants (Basel, Switzerland) · 2025
    Article
  14. Proteomics-based multi-omics reveals mPlant communications · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Landscape and mCell genomics · 2025
    Article
  19. Article
  20. Article

196 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Justin W WalleyDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA. Department of Plant Pathology and Microbiology, Iowa State University, Ames, IA 50011, USA.
Ryan C SartorDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Zhouxin ShenDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Robert J SchmitzPlant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Kevin J WuDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Mark A UrichPlant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Joseph R NeryGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Laurie G SmithDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
James C SchnableDepartment of Agronomy and Horticulture, University of Nebraska, Lincoln, NE 68583, USA.
Joseph R EckerPlant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Steven P BriggsDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA. sbriggs@ucsd.edu.
University of California, San Diego · USSalk Institute for Biological Studies · USUniversity of Nebraska–Lincoln · US

Funding

Mechanisms by which a fungal HDAC inhibitor suppresses innate immunity in maizeF32GM096707 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WALLEY, JUSTIN WILLIAM · 2011 to 2012
$101k
Howard Hughes Medical InstituteNIGMS NIH HHS F32 GM096707NIGMS NIH HHS F32GM096707
6 · The paper itself

Abstract

Coexpression networks and gene regulatory networks (GRNs) are emerging as important tools for predicting functional roles of individual genes at a system-wide scale. To enable network reconstructions, we built a large-scale gene expression atlas composed of 62,547 messenger RNAs (mRNAs), 17,862 nonmodified proteins, and 6227 phosphoproteins harboring 31,595 phosphorylation sites quantified across maize development. Networks in which nodes are genes connected on the basis of highly correlated expression patterns of mRNAs were very different from networks that were based on coexpression of proteins. Roughly 85% of highly interconnected hubs were not conserved in expression between RNA and protein networks. However, networks from either data type were enriched in similar ontological categories and were effective in predicting known regulatory relationships. Integration of mRNA, protein, and phosphoprotein data sets greatly improved the predictive power of GRNs.

Indexed as

Gene Regulatory NetworksPhosphoproteinsPhosphorylationPlant ProteinsProteomeProteomicsRNA, MessengerTranscriptomeZea maysPhosphoproteinsPlant ProteinsProteomeRNA, Messenger

Identifiers

PMID27540173
PMCPMC5808982
OpenAlexW2515922456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.