Evidence map›Paper›PMID 27540043›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2017

Transitioning Preterm Infants From Parenteral Nutrition: A Comparison of 2 Protocols.

Malki Miller, Keyur Donda, Alok Bhutada, Deepa Rastogi, Shantanu Rastogi

Abstract readComparative Study
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Analysis of factors driving variations in neonatal parenteral nutrition over a decade: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
  3. AI to predict extrauterine growth restriction during transitional nutrition of preterm infants: a retrospective study.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Observational
  4. Feeding Approach to Optimizing Nutrition in Infants with Congenital Heart Disease.Journal of cardiovascular development and disease · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. "Extrauterine growth restriction" and "postnatal growth failure" are misnomers for preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malki Miller1 Department of Nutrition, Maimonides Infants and Children's Hospital, Brooklyn, New York, USA.
Keyur Donda2 Division of Neonatology, Maimonides Infants and Children's Hospital, Brooklyn, New York, USA.
Alok Bhutada2 Division of Neonatology, Maimonides Infants and Children's Hospital, Brooklyn, New York, USA.
Deepa Rastogi3 Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York, USA.
Shantanu Rastogi2 Division of Neonatology, Maimonides Infants and Children's Hospital, Brooklyn, New York, USA.

Funding

Genetic and Epigenetic Determinants of Pediatric Obesity-Associated AsthmaK23HL118733 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI RASTOGI, DEEPA · 2014 to 2018
$893k
NHLBI NIH HHS K23 HL118733
6 · The paper itself

Abstract

backgroundGrowth in preterm infants is compromised during the transition phase of nutrition, when parenteral nutrition (PN) volumes are weaned with advancing enteral nutrition (EN) feeds, likely due to suboptimal nutrient intakes during this time. We implemented new PN guidelines designed to maintain optimal nutrient intakes during the transition phase and compared growth outcomes of this cohort with a control group. MATERIALS AND

methodsA chart review was conducted on infants born <32 weeks' gestation, before (control group) and after (study group) a new transition PN protocol was implemented in the neonatal intensive care unit. Weight parameters and nutrient intakes were calculated for the transition phase and compared between the 2 groups.

resultsDemographic and clinical characteristics of the 2 groups were comparable except for higher rates of sepsis in control group. Weight-for-age z scores at birth, at 1 week of life, and at the start of the transition phase were similar. At the end of the transition phase, infants in the study group had significantly higher z scores compared with the control group, even when corrected for sepsis, a difference that persisted at 35 weeks' gestation. During the transition phase, study infants gained 16.1 ± 4.6 g/kg/d compared with 13.2 ± 5.4 g/kg/d in control group ( P < .001). Similar results were observed in the subset of expressed breastmilk-only fed infants (15.9 ± 4.6 g/kg/d in the study group compared with 13.2 ± 5.4 g/kg/d in the control group, P < .004).

conclusionOptimizing nutrition by the use of concentrated PN during the transition phase to maintain appropriate nutrient intakes improves growth rates in preterm infants.

Indexed as

Enteral NutritionParenteral NutritionBody WeightCase-Control StudiesDietary ProteinsEnergy IntakeFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleMilk, HumanNutritional RequirementsDietary Proteinsenteral nutritionlife cycleneonatesnutritionnutrition support practiceoutcomes research/qualityparenteral nutrition

Identifiers

PMID27540043
PMCPMC5407937

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.