Evidence map›Paper›PMID 27539974›Full record

Observational studyAmerican journal of preventive medicine2016

Ideal Cardiovascular Health and Incident Cardiovascular Events: The Jackson Heart Study.

Mark J Ommerborn, Chad T Blackshear, DeMarc A Hickson, Michael E Griswold, Japneet Kwatra, Luc Djoussé, Cheryl R Clark

Abstract readObservational Study
In one paragraph

Observational study in American journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 5 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 5 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mark J OmmerbornCenter for Community Health and Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.
Chad T BlackshearCenter of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, Mississippi.
DeMarc A HicksonCenter for Research, Evaluation and Environmental and Policy Change, My Brother's Keeper, Inc., Jackson, Mississippi; Department of Epidemiology and Biostatistics, Jackson State University, Jackson, Mississippi.
Michael E GriswoldCenter of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, Mississippi.
Japneet KwatraCenter for Community Health and Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.
Luc DjousséDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Division of Aging, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Boston VA Healthcare System, Boston, Massachusetts;
Cheryl R ClarkCenter for Community Health and Health Equity, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Division of General Medicine and Primary Care, Brigham and Women's Faulkner Hospitalist Program, Boston, Massachusetts. Electronic address: crclark@partners.org.
Brigham and Women's Hospital · USUniversity of Mississippi Medical Center · USJackson State University · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI Jacques J. Kessl · 2012 to 2026
$60.2M
JACKSON HEART STUDY--EXAM CENTERN01HC095171 · HC · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI JONES, DANIEL W · 1999 to 2001
$4.6M
Geographic Variation in Cardiovascular Inflammation in Middle-aged & Elderly PopuK08AG032357 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, CHERYL RENEE · 2009 to 2013
$634k
JACKSON HEART STUDY--TRAINING CENTERN01HC095172 · HC · TOUGALOO COLLEGE · PI SRINIVASAN, ASOKA · 1999 to 2001
$516k
Development of a humanized anti-CD47 antibody for treatment of tissue ischemia.R41HL095172 · NHLBI · VASCULOX, INC. · PI FRAZIER, WILLIAM A · 2009 to 2009
$198k
JACKSON HEART STUDY-N01HC95170N01HC095170 · HC · JACKSON STATE UNIVERSITY · PI TAYLOR, HERMAN ALFRED · 1999 to 2006
$20k
NHLBI NIH HHS N01 HC095170NHLBI NIH HHS N01 HC095171NHLBI NIH HHS N01 HC095172NIA NIH HHS K08 AG032357NIGMS NIH HHS P20 GM103476
6 · The paper itself

Abstract

introductionThe epidemiology of American Heart Association ideal cardiovascular health (CVH) metrics has not been fully examined in African Americans. This study examines the associations of CVH metrics with incident cardiovascular disease (CVD) in the Jackson Heart Study, a longitudinal cohort study of CVD in African Americans.

methodsJackson Heart Study participants without CVD (n=4,702) were followed prospectively between 2000 and 2011. Incidence rates and Cox proportional hazard ratios estimated risks for incident CVD (myocardial infarction, stroke, cardiac procedures, and CVD mortality) associated with seven CVH metrics by sex. Analyses were performed in 2015.

resultsParticipants were followed for a median of 8.3 years; none had ideal health on all seven CVH metrics. The prevalence of ideal health was low for nutrition, physical activity, BMI, and blood pressure metrics. The age-adjusted CVD incidence rate (IR) per 1,000 person years was highest for individuals with the least ideal health metrics: zero to one (IR=12.5, 95% CI=9.7, 16.1), two (IR=8.2, 95% CI=6.5, 10.4), three (IR=5.7, 95% CI=4.2, 7.6), and four or more (IR=3.4, 95% CI=2.0, 5.9). Adjusting for covariates, individuals with four or more ideal CVH metrics had lower risks of incident CVD compared with those with zero or one ideal CVH metric (hazard ratio, 0.29; 95% CI=0.17, 0.52; p<0.001).

conclusionsAfrican Americans with more ideal CVH metrics have lower risks of incident CVD. Comprehensive preventive behavioral and clinical supports should be intensified to improve CVD risk for African Americans with few ideal CVH metrics.

Indexed as

AdultAgedCardiovascular DiseasesCohort StudiesFemaleHumansIncidenceMaleMiddle AgedMississippi

Identifiers

PMID27539974
PMCPMC5152585
OpenAlexW2507295570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.