Evidence map›Paper›PMID 27539584›Full record

ArticleJournal of natural medicines2017

Constituents from the leaves of Clausena lansium and their anti-inflammatory activity.

De-Yang Shen, Ping-Chung Kuo, Shiow-Chyn Huang, Tsong-Long Hwang, Yu-Yi Chan, Po-Chuen Shieh, Nguyen Thi Ngan, Tran Dinh Thang, Tian-Shung Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Chemical Constituents andLife (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bioactive Compounds from the Stems of Clausena lansium.Molecules (Basel, Switzerland) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

De-Yang ShenSchool of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Ping-Chung KuoSchool of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Shiow-Chyn HuangDepartment of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan, 71710, Taiwan, ROC.
Tsong-Long HwangGraduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, 333, Taiwan, ROC.
Yu-Yi ChanDepartment of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, 71005, Taiwan.
Po-Chuen ShiehDepartment of Pharmacy, Tajen University, Pingtung, 90741, Taiwan, ROC.
Nguyen Thi NganDepartment of Chemistry, Vinh University, Vinh City, Vietnam.
Tran Dinh ThangDepartment of Chemistry, Vinh University, Vinh City, Vietnam.
Tian-Shung WuSchool of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan, ROC. tswu@mail.ncku.edu.tw.
National Cheng Kung University Hospital · TWTajen University · TWVinh University · VNChia Nan University of Pharmacy and Science · TWSouthern Taiwan University of Science and Technology · TWTaoyuan Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Five new acyclic amides, clausenalansamides C-G (1-5), clausenaline G (6) and (±)-5-(4-methylphenyl)-γ-valerolactone (7) reported from the natural source for the first time, were characterized from the leaves of Clausena lansium. Their structures were established by spectroscopic and spectrometric methods, and the absolute configurations of new compounds 1-5 were determined by electronic circular dichroism and single-crystal X-ray diffraction analyses. Eighteen compounds were evaluated for their anti-inflammatory activity and only imperatorin (11) and wampetin (12) displayed significant inhibition of fMLP/CB-induced superoxide anion generation with IC

Indexed as

Anti-Inflammatory AgentsClausenaMolecular StructurePlant LeavesAnti-Inflammatory AgentsAnti-inflammatoryClausenalansamideElectronic circular dichroismSingle-crystal X-ray diffraction analysisSuperoxide anion generation

Identifiers

PMID27539584
OpenAlexW2512630702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.