ReviewNature reviews. Endocrinology2017
Long-term metabolic risk among children born premature or small for gestational age.
Review in Nature reviews. Endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
142 citing papers in PubMed, 11 syntheses or guidelines pooled it, 256 citations in OpenAlex.
- An assessment of methods for measuring body composition in full-term infants: A systematic review.Pediatric research · 2026Pooled it
- Early cessation of exclusive breastfeeding and associated factors in Ethiopia: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Research focus and emerging trends of the gut microbiome and infant: a bibliometric analysis from 2004 to 2024.Frontiers in microbiology · 2024Pooled it
- Diagnosis or prognosis? An umbrella review of mid-trimester cervical length and spontaneous preterm birth.BJOG : an international journal of obstetrics and gynaecology · 2023Pooled it
- International Consensus Guideline on Small for Gestational Age: Etiology and Management From Infancy to Early Adulthood.Endocrine reviews · 2023Guideline
- Effect of maternal vitamin D status on risk of adverse birth outcomes: a systematic review and dose-response meta-analysis of observational studies.European journal of nutrition · 2022Pooled it
- The effect of unemployment and post-natal care on the exclusive breast-feeding practice of women in Ethiopia: a systematic review and meta-analysis.Reproductive health · 2022Pooled it
- A systematic review on estimating population attributable fraction for risk factors for small-for-gestational-age births in 81 low- and middle-income countries.Journal of global health · 2022Pooled it
- Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and meta-analysis.PLoS medicine · 2019Pooled it
- Education of family members to support weaning to solids and nutrition in infants born preterm.The Cochrane database of systematic reviews · 2019Pooled it
- Risk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses.PloS one · 2018Pooled it
- The effect of mHealth on childhood vaccination and its associated factors among South Ethiopian mothers: a cluster randomized controlled trial.Scientific reports · 2025Trial
- A Phase 2 Study of PEGylated Recombinant Human Growth Hormone for 52 Weeks in Short Children Born Small for Gestational Age in China.Clinical endocrinology · 2025Trial
- Hypertensive disorders of pregnancy contribute to developmental and metabolic multimorbidity in preterm infants.Nature communications · 2026Article
- The effect of antenatal common mental disorders on infant birth weight at the Dabat health and demographic surveillance site, Northwest Ethiopia: a community-based cohort study.BMC pregnancy and childbirth · 2026Article
- Efficacy and safety of GH treatment in Japanese pediatric patients withClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Article
- Breastfeeding in term and preterm infants with and without growth restriction: A 50-year analysis of incidence and duration.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Preterm Birth, Fetal Growth Restriction and Early Postnatal Body Mass Index Normalisation Predict Adult Anthropometry.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Slight acceleration in podocyte mRNA loss in preterm-born children aged 3-5 years.Pediatric nephrology (Berlin, Germany) · 2026Article
- Optimal weight gain to reduce obesity risk in preterm infants in a National cohort study.Scientific reports · 2026Article
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accumulating evidence suggests that both the intrauterine environment and growth during early life can influence the development of chronic noncommunicable diseases, such as type 2 diabetes mellitus and cardiovascular disease, in adulthood. Here, we review the available human data supporting increased metabolic risk among children born premature or small for gestational age; the adrenal and pubertal modifications that contribute to this risk; metabolic changes that occur during adolescence and early adulthood; and approaches to potentially modify or decrease risk of metabolic disease. The risks associated with delivery at term or preterm are compared for each period of life. Knowledge of these associations is fundamental for the paediatric community to develop preventive strategies early during postnatal life.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.