Incidence of Mucinous Metaplasia in the Prostate of FVB/N Mice (Mus musculus).

Leena Latonen, Paula Kujala, Tapio Visakorpi

Open access · greenAbstract read

In one paragraph

Article in Comparative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 34% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

Phenotypic characteristics of commonly used inbred mouse strains.Journal of molecular medicine (Berlin, Germany) · 2020
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Leena LatonenInstitute of Biosciences and Medical Technology (BioMediTech), University of Tampere, Fimlab Laboratories, Tampere University Hospital, Tampere, Finland. leena.latonen@uta.fi.

Paula KujalaFimlab Laboratories, Tampere University Hospital, Tampere, Finland.

Tapio VisakorpiInstitute of Biosciences and Medical Technology (BioMediTech), University of Tampere, Fimlab Laboratories, Tampere University Hospital, Tampere, Finland.

Tampere University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate epithelium in mice is considered to be relatively resistant to aged-related changes, as compared with human prostate epithelium, which is prone to spontaneous hyperplasia and cancer, for example. In addition, the incidence of metaplasia in mouse prostate typically is considered to be low. Here we report the incidence of mucinous metaplasia in the prostates of wild-type FVB/N mice. Our histologic study shows that mucinous metaplasia involving goblet cells occurs much more frequently (incidence as high as 50%) in the prostates of aged mice (17-24 mo) than has been reported previously. Mucinous metaplasia in the prostates of laboratory mice may be considerably more frequent than previously appreciated.

Indexed as

AgingAnimalsEpitheliumGoblet CellsMaleMetaplasiaMiceMice, Inbred StrainsProstateSpecies Specificity

Identifiers

PMID27538859

PMCPMC4983170

OpenAlexW2519926316

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.