Evidence map›Paper›PMID 27538722›Full record

ArticleAmerican journal of hypertension2016

The Mediation of Racial Differences in Hypertension by Sleep Characteristics: Chicago Area Sleep Study.

Laura J Rasmussen-Torvik, Peter John D De Chavez, Kiarri N Kershaw, Samantha E Montag, Kristen L Knutson, Kwang-Youn A Kim, Phyllis C Zee, Mercedes R Carnethon

Abstract readComparative Study
In one paragraph

Article in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Habitual sleep as a contributor to racial differences in cardiometabolic risk.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Trial
  2. Review
  3. Review
  4. Article
  5. Disparities in sleep care and cardiovascular outcomes: defining the problem and implementing solutions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  6. Article
  7. Article
  8. CARDIA sleep ancillary study: study design and methods.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
  9. Article
  10. Does air pollution contribute to urban-rural disparity in male lung cancer diseases in China?Environmental science and pollution research international · 2022
    Article
  11. Article
  12. Article
  13. Sleep and Resistant Hypertension.Current hypertension reports · 2019
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura J Rasmussen-TorvikDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Peter John D De ChavezDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Kiarri N KershawDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Samantha E MontagDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Kristen L KnutsonDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Kwang-Youn A KimDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Phyllis C ZeeDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Mercedes R CarnethonDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Funding

Autonomic, Endothelial, and Inflammatory Correlates of Sleep DurationR01HL092140 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARNETHON, MERCEDES RENEE · 2009 to 2012
$2.0M
NHLBI NIH HHS R01 HL092140
6 · The paper itself

Abstract

backgroundRacial disparities in hypertension prevalence in the United States are established. Given our understanding of racial and ethnic disparities in sleep characteristics and demonstrated associations between sleep characteristics and hypertension, we tested whether sleep characteristics mediated racial disparities in hypertension.

methodsAnalyses were performed in the Chicago Area Sleep Study, a population-based cohort study of 154 Blacks, 128 Whites, 103 Hispanics, and 109 Asians without obstructive sleep apnea. Participants underwent 7 days of wrist actigraphy monitoring. Algorithms were used to determine sleep duration and sleep maintenance (the percent of sleep in the sleep period). Hypertension was determined as systolic blood pressure >140mm Hg or diastolic blood pressure >90mm Hg or the use of antihypertensive medications. We estimated sample prevalence ratios for hypertension before and after adjustment for sleep characteristics and also conducted mediation analysis.

resultsThe sample prevalence of hypertension was highest in Blacks (36%), followed by Hispanics (14%), Asians (8%), and Whites (5%). The sample prevalence ratio for hypertension for Blacks vs. Whites was 5.52 (95% confidence interval (CI): 2.36, 13.23) after adjusting for age, sex, and education. Adjustment for sleep duration had no influence on the effect estimate, but adjustment for sleep maintenance attenuated the sample prevalence ratio to 4.55 (95% CI: 1.91, 11.14). Sleep maintenance mediated 11.4% of the difference in hypertension prevalence between Blacks and Whites in this sample.

conclusionsSleep maintenance mediated a small but significant portion of the disparity in hypertension between Blacks and Whites. Future research should investigate the mechanisms underlying these findings.

Indexed as

AsianBlack or African AmericanBlood PressureHealth Status DisparitiesHispanic or LatinoSleepWhite PeopleAdultAntihypertensive AgentsChicagoCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedAntihypertensive Agentsblood pressurehypertensionmediationracial disparities.sleep maintenance

Identifiers

PMID27538722
PMCPMC5966848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.