ArticleNeurocritical care2017
Tracheostomy or Not: Prediction of Prolonged Mechanical Ventilation in Guillain-Barré Syndrome.
Article in Neurocritical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Guidelines for Neuroprognostication in Adults with Guillain-Barré Syndrome.Neurocritical care · 2023Guideline
- Risk Factors for Prolonged Mechanical Ventilation and Weaning Failure: A Systematic Review.Respiration; international review of thoracic diseases · 2022Pooled it
- Patient Outcomes Among Medicare Beneficiaries With Guillain-Barré Syndrome.Journal of the peripheral nervous system : JPNS · 2026Article
- Beyond ventilator weaning: rethinking the role of tracheostomy in Guillain-Barré syndrome.Annals of intensive care · 2026Article
- Challenges in managing prolonged intensive care unit stay for Guillain-Barré syndrome-acute motor axonal neuropathy variant.SAGE open medical case reports · 2026Article
- Effects of direct tracheostomy on ventilator weaning in patients intubated for Guillain-Barré syndrome.Annals of intensive care · 2026Article
- Guillain-Barré Syndrome in Older People-A Case Report and Literature Review.Diseases (Basel, Switzerland) · 2025Review
- Guillain-Barré syndrome.BJA education · 2025Review
- Critical insights for intensivists on Guillain-Barré syndrome.Annals of intensive care · 2025Review
- Long-term outcomes of patients affected by Guillain-Barré syndrome in Colombia after the Zika virus epidemic.Journal of the neurological sciences · 2024Article
- Predictors of respiratory failure in Guillain-Barré syndrome: a 22 year cohort study from a single Italian centre.European journal of neurology · 2024Article
- A data-driven model for early prediction of need for invasive mechanical ventilation in pediatric intensive care unit patients.PloS one · 2023Observational
- Risk Factors for Mechanical Ventilation in Patients with Guillain-Barré Syndrome.Neurocritical care · 2022Article
- International Validation of the Erasmus Guillain-Barré Syndrome Respiratory Insufficiency Score.Annals of neurology · 2022Article
- Case Report: Guillain-Barré Syndrome as Primary Presentation of Systemic Lupus Erythematosus (SLE-GBS) in a Teenage Girl.Frontiers in pediatrics · 2022Article
- Intensive Care and Treatment of Severe Guillain-Barré Syndrome.Frontiers in pharmacology · 2021Review
- Effect of Early Tracheostomy on Mortality of Mechanically Ventilated Patients with Guillain-Barré Syndrome: A Nationwide Observational Study.Neurocritical care · 2020Observational
- Successful treatment of a 12-year-old boy with Guillain-Barré syndrome requiring tracheostomy due to respiratory muscle paralysis: A case report.Experimental and therapeutic medicine · 2020Article
- A Predictive Model for Respiratory Failure and Determining the Risk Factors of Prolonged Mechanical Ventilation in Children with Guillain-Barre Syndrome.Iranian journal of child neurology · 2020Article
- Diagnosis and management of Guillain-Barré syndrome in ten steps.Nature reviews. Neurology · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRespiratory insufficiency occurs in 20 % of Guillain-Barré syndrome (GBS) patients, and the duration of mechanical ventilation (MV) ranges widely. We identified predictors of prolonged MV to guide clinical decision-making on tracheostomy.
methodsWe analyzed prospectively collected data from 552 patients with GBS in the context of two clinical trials and three cohort studies in The Netherlands. Potential predictors for prolonged MV, defined as duration of ≥14 days, were considered using crosstabs. Selected predictors were analyzed using Cox regression analysis.
resultsOn a total of 150 (27 %) patients requiring MV, 106 (71 %) patients needed prolonged MV. The median duration of MV was 28 days (Interquartile Range [IQR] 12-60 days). The strongest observed predictors of prolonged MV were muscle weakness and axonal degeneration or unexcitable nerves on nerve conduction studies. Patients who are unable to lift the arms from the bed (bilateral Medical Research Council [MRC] of deltoid muscles of 0-2) at 1 week after intubation have an 87 % chance to require prolonged MV versus 69 % in patients who are able to lift the arms from the bed (bilateral MRC of deltoid muscles of 3-10). Patients in this last group who had axonal degeneration or unexcitable nerves on nerve conduction studies also have a 90 % chance to require prolonged MV.
conclusionsVentilated GBS patients who are unable to lift the arms from the bed and patients who have axonal degeneration or unexcitable nerves at 1 week are at high risk of prolonged MV, and tracheostomy should be considered in these patients.
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