Evidence map›Paper›PMID 27538374›Full record

Trial reportBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2016

Trajectories of Quality of Life after Hematopoietic Cell Transplantation: Secondary Analysis of Blood and Marrow Transplant Clinical Trials Network 0902 Data.

Heather S L Jim, Steven K Sutton, Brent J Small, Paul B Jacobsen, William A Wood, Jennifer M Knight, Navneet S Majhail, Karen L Syrjala, Stephanie J Lee

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Effects of expressive helping writing during stem cell transplant: Randomized controlled trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Trial
  2. Trial
  3. Age as a moderator of neurocognitive performance in patients with large B-cell lymphoma treated with axicabtagene ciloleucel.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Short-Term Impact of Hematopoietic Stem Cell Transplantation on Depressive Behavior, Cognition and Quality of Life in Leukemia Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Evaluation of quality of life and its influencing factors after transplantation of leukemia patients based on SF-36 score: a cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida. Electronic address: heather.jim@moffitt.org.
Steven K SuttonDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida.
Brent J SmallDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida; School of Aging Studies, University of South Florida, Tampa, Florida.
Paul B JacobsenDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
William A WoodDivision of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
Jennifer M KnightDepartments of Psychiatry and Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Navneet S MajhailBlood and Marrow Transplant Program, Cleveland Clinic, Cleveland, Ohio.
Karen L SyrjalaClinical Research Division, Fred Hutchison Cancer Research Center, Seattle, Washington.
Stephanie J LeeClinical Research Division, Fred Hutchison Cancer Research Center, Seattle, Washington.
Moffitt Cancer Center · USFred Hutch Cancer Center · USCleveland Clinic · USMedical College of Wisconsin · USUniversity of North Carolina at Chapel Hill · USUniversity of South Florida · US

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
Internet Studies to Enhance Long Term Survivorship after Hematologic MalignancyR01CA160684 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SYRJALA, KAREN LESLIE · 2011 to 2015
$3.4M
Blood & Marrow Clinical Trials Network - Hutchinson Center Core Clinical SitU10HL069246 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI APPELBAUM, FREDERICK · 2011 to 2016
$1.1M
Sargrastim and Plerixafor vs. Filgrastim for Allogeneic Stem Cell MobilizationU10HL109137 · NHLBI · WASHINGTON UNIVERSITY · PI WESTERVELT, PETER · 2011 to 2016
$937k
NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA160684NCI NIH HHS U24 CA076518NHLBI NIH HHS U10 HL069246NHLBI NIH HHS U10 HL069294NHLBI NIH HHS U10 HL109137
6 · The paper itself

Abstract

Quality of life is increasingly recognized as an important secondary endpoint of hematopoietic cell transplantation (HCT). The current study examined the extent to which attrition results in biased estimates of patient quality of life. The study also examined whether patients differ in terms of trajectories of quality of life in the first 6 months after transplantation. A secondary data analysis was conducted of 701 participants who enrolled in the Blood and Marrow Transplantation Clinical Trials Network 0902 trial. Participants completed the Medical Outcomes Study Short Form 36, a measure of quality of life, before undergoing transplantation and again 100 days and 180 days after transplantation. Results indicated that attrition resulted in slightly biased overestimates of quality of life but the amount of overestimation remained stable over time. Patients could be grouped into 3 distinct classes based on physical quality of life: (1) low and stable; (2) average and declining, then stable; and (3) average and stable. Four classes of patients emerged for mental quality of life: (1) low and stable; (2) average, improving, then stable; (3) higher than average (by almost 1 SD) and stable; and (4) average and stable. Taken together, these data provide a more comprehensive understanding of quality of life that can be used to educate HCT recipients and their caregivers.

Indexed as

Quality of LifeAdolescentAdultAgedBiasBone Marrow TransplantationFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedSurveys and QuestionnairesTime FactorsYoung AdultHematopoietic stem cell transplantationQuality of life

Identifiers

PMID27538374
PMCPMC5068568
OpenAlexW2510629501

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.