Evidence map›Paper›PMID 27537902›Full record

SynthesisInternational journal of environmental research and public health2016

Comparison of the Ability to Predict Mortality between the Injury Severity Score and the New Injury Severity Score: A Meta-Analysis.

Qiangyu Deng, Bihan Tang, Chen Xue, Yuan Liu, Xu Liu, Yipeng Lv, Lulu Zhang

Registry-linked trialAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06705959 (Can NISS or ISS Better Predict Mortality in Blunt Trauma Patients? A Prospective Study), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06705959 recruitingnot on this mapstarted 2025, after this paper: background citation

Can NISS or ISS Better Predict Mortality in Blunt Trauma Patients? A Prospective Study

TypeobservationalSponsorAl-Nahrain UniversityRan2025 to 2025Enrolled200ConditionsTrauma
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A different perspective in trauma patients: can pan-immune-inflammation value (PIV) predict mortality?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  5. Predictive performance of ISS and NISS for clinical outcomes in severely injured trauma patients: a retrospective registry study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  6. Observational
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Risk factors for rehospitalization after trauma: a follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiangyu DengDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. smmudqy@163.com.
Bihan TangDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. mangotangbihan@126.com.
Chen XueDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. xue1990chen@163.com.
Yuan LiuDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. yawnlau@126.com.
Xu LiuDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. xuliuaqua@126.com.
Yipeng LvDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. happylvyipeng@163.com.
Lulu ZhangDepartment of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China. zllrmit@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDescription of the anatomical severity of injuries in trauma patients is important. While the Injury Severity Score has been regarded as the "gold standard" since its creation, several studies have indicated that the New Injury Severity Score is better. Therefore, we aimed to systematically evaluate and compare the accuracy of the Injury Severity Score and the New Injury Severity Score in predicting mortality.

methodsTwo researchers independently searched the PubMed, Embase, and Web of Science databases and included studies from which the exact number of true-positive, false-positive, false-negative, and true-negative results could be extracted. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies checklist criteria. The meta-analysis was performed using Meta-DiSc. Meta-regression, subgroup analyses, and sensitivity analyses were conducted to determine the source(s) of heterogeneity and factor(s) affecting the accuracy of the New Injury Severity Score and the Injury Severity Score in predicting mortality.

resultsThe heterogeneity of the 11 relevant studies (total n = 11,866) was high (I² > 80%). The meta-analysis using a random-effects model resulted in sensitivity of 0.64, specificity of 0.93, positive likelihood ratio of 5.11, negative likelihood ratio of 0.27, diagnostic odds ratio of 27.75, and area under the summary receiver operator characteristic curve of 0.9009 for the Injury Severity Score; and sensitivity of 0.71, specificity of 0.87, positive likelihood ratio of 5.22, negative likelihood ratio of 0.20, diagnostic odds ratio of 24.74, and area under the summary receiver operating characteristic curve of 0.9095 for the New Injury Severity Score.

conclusionThe New Injury Severity Score and the Injury Severity Score have similar abilities in predicting mortality. Further research is required to determine the appropriate use of the Injury Severity Score or the New Injury Severity Score based on specific patient condition and trauma type.

Indexed as

Injury Severity ScoreAdolescentAdultFemaleForecastingHumansMaleROC CurveSensitivity and SpecificityWounds and InjuriesYoung AdultInjury Severity Scoremeta-analysismortalityNew Injury Severity Score

Identifiers

PMID27537902
PMCPMC4997511

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.