ArticleMolecules (Basel, Switzerland)2016
Phytochemical Profile and Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum and Fortunella margarita.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 125 citations in OpenAlex.
- Chemical composition and insecticidal activity of essential oils from Citrus limon, Citrus aurantium, and Citrus margarita against Musca domestica.Scientific reports · 2026Article
- Microbial communities in the rhizosphere of three Mentha species: Links to soil properties and essential oil profiles.PloS one · 2026Article
- Review
- Evaluation of Polyphenolic Compounds Common in Greek Medicinal Plants for Their Antioxidant Effects and Antiviral Activity Against Dengue and Yellow Fever Viruses.Antioxidants (Basel, Switzerland) · 2025Article
- Anise and Fennel Essential Oils and Their Combination as Natural and Safe Housefly Repellents.Insects · 2024Article
- Chemical Profile of Kumquat (Foods (Basel, Switzerland) · 2024Article
- A Review of Botanical Extracts with Repellent and Insecticidal Activity and Their Suitability for Managing Mosquito-Borne Disease Risk in Mexico.Pathogens (Basel, Switzerland) · 2024Review
- Effects of Mint Oils on the Human Oral Microbiome: A Pilot Study.Microorganisms · 2024Article
- Chemical Characterization of the Essential Oil Compositions ofMolecules (Basel, Switzerland) · 2024Article
- Article
- Assessment of the Anti-Amyloidogenic Properties of Essential Oils and Their Constituents in Cells Using a Whole-Cell Recombinant Biosensor.Brain sciences · 2023Article
- Exploring Plants with Flowers: From Therapeutic Nutritional Benefits to Innovative Sustainable Uses.Foods (Basel, Switzerland) · 2023Review
- The comparative perspective of phytochemistry and biological properties of the Apiaceae family plants.Scientific reports · 2023Article
- Resistance, Tolerance, Virulence and Bacterial Pathogen Fitness-Current State and Envisioned Solutions for the Near Future.Pathogens (Basel, Switzerland) · 2023Review
- Nanostructured Lipid Carrier-Based Gel for Repurposing Simvastatin in Localized Treatment of Breast Cancer: Formulation Design, Development, and In Vitro and In Vivo Characterization.AAPS PharmSciTech · 2023Article
- Inhibitory Activity of Essential Oils ofAntibiotics (Basel, Switzerland) · 2023Article
- Emerging Biopharmaceuticals fromMolecules (Basel, Switzerland) · 2023Review
- Anti-inflammatory, immunomodulatory and anti-oxidant effects ofIranian journal of basic medical sciences · 2023Review
- Natural essential oils as a new therapeutic tool in colorectal cancer.Cancer cell international · 2022Review
- Nanomedicine as an Emerging Technology to Foster Application of Essential Oils to Fight Cancer.Pharmaceuticals (Basel, Switzerland) · 2022Review
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural products, known for their medicinal properties since antiquity, are continuously being studied for their biological properties. In the present study, we analyzed the composition of the volatile preparations of essential oils of the Greek plants Ocimum basilicum (sweet basil), Mentha spicata (spearmint), Pimpinella anisum (anise) and Fortunella margarita (kumquat). GC/MS analyses revealed that the major components in the essential oil fractions, were carvone (85.4%) in spearmint, methyl chavicol (74.9%) in sweet basil, trans-anethole (88.1%) in anise, and limonene (93.8%) in kumquat. We further explored their biological potential by studying their antimicrobial, antioxidant and antiproliferative activities. Only the essential oils from spearmint and sweet basil demonstrated cytotoxicity against common foodborne bacteria, while all preparations were active against the fungi Saccharomyces cerevisiae and Aspergillus niger. Antioxidant evaluation by DPPH and ABTS radical scavenging activity assays revealed a variable degree of antioxidant potency. Finally, their antiproliferative potential was tested against a panel of human cancer cell lines and evaluated by using the sulforhodamine B (SRB) assay. All essential oil preparations exhibited a variable degree of antiproliferative activity, depending on the cancer model used, with the most potent one being sweet basil against an in vitro model of human colon carcinoma.
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