ReviewMolecules (Basel, Switzerland)2016
Bioactive Thiazine and Benzothiazine Derivatives: Green Synthesis Methods and Their Medicinal Importance.
Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 100 citations in OpenAlex.
- Synthesis, Spectroscopic Characterization, Molecular Docking Studies Toward the GABAPharmaceuticals (Basel, Switzerland) · 2026Article
- Molecular insights into the bioactivity of H-thiazine compounds against breast cancer cells: a computational study.In silico pharmacology · 2026Article
- FeMolecular diversity · 2025Article
- Exploring the Diverse Therapeutic Applications of 1, 3-Thiazine: A Comprehensive Review.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025Review
- A Convenient One-Pot Synthesis of Novel Benzimidazole-Thiazinone Derivatives and Their Antimicrobial Activity.Antibiotics (Basel, Switzerland) · 2024Article
- Green Synthesis of 2-Mercapto 5,6-Dihydro-4Molecules (Basel, Switzerland) · 2024Article
- Pd-, Cu-, and Ni-Catalyzed Reactions: A Comprehensive Review of the Efficient Approaches towards the Synthesis of Antibacterial Molecules.Pharmaceuticals (Basel, Switzerland) · 2024Review
- The Application of Green Solvents in the Synthesis ofInternational journal of molecular sciences · 2024Review
- Article
- Green Synthetic Methods of Oxazine and Thiazine Scaffolds as Promising Medicinal Compounds: A Mini-review.Current organic synthesis · 2024Review
- Design, synthesis, and evaluation of 1,4-benzothiazine-3-one containing bisamide derivatives as dual inhibitors ofFrontiers in chemistry · 2024Article
- Green Synthetic Strategies and Pharmaceutical Applications of Thiazine and its Derivatives: An Updated Review.Current pharmaceutical biotechnology · 2024Review
- The Multifaceted Opportunities Provided by the Pheomelanin-Inspired 1,4-Benzothiazine Chromophore: A Still-Undervalued Issue.Molecules (Basel, Switzerland) · 2023Review
- The Benzothiazine Core as a Novel Motif for DNA-Binding Small Molecules.Molecules (Basel, Switzerland) · 2023Article
- Antiparasitic Activity of Fluorophenyl-Substituted Pyrimido[1,2-Biomedicines · 2023Article
- Seeking heterocyclic scaffolds as antivirals against dengue virus.European journal of medicinal chemistry · 2022Review
- Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cells.Pharmacological reports : PR · 2022Article
- Gold-Catalyzed 1,3-Thiazine Formation and Uncommon Tautomer Isolation.The Journal of organic chemistry · 2022Article
- Design, Synthesis and Pharmacological Evaluation of 2-(3-BenzoyI-4-Hydroxy-1,1-Dioxido-2H-Benzo[e][1,2]thiazin-2-yI)-N-(2-Bromophenyl) Acetamide as Antidiabetic Agent.Drug design, development and therapy · 2022Article
- Derivatives of benzo-1,4-thiazine-3-carboxylic acid and the corresponding amino acid conjugates.Beilstein journal of organic chemistry · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thiazines are a group of heterocyclic organic compounds that are still largely unexplored for their pharmacological activities. There are different available methods for the synthesis of thiazine derivatives in the literature. In this review, we discuss available methods of thiazine preparation through green synthesis methods. Beside their synthesis, many thiazine derivatives are biologically active and play an important role in the treatment of various diseases and show promising results of varying degrees, where they act as antibacterial, antifungal, antitumor, antimalarial, antineoplastic, antiviral, anti-inflammatory, analgesic and anticancer agents and thus they represent an interesting class of heterocyclic medicinal compounds worthy of further exploration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.