Observational studyMedicine2016
The positive duration of varicella zoster immunoglobulin M antibody test in herpes zoster.
Observational study in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Review
- Evidence of Varicella Zoster Virus Reactivation in Children With Arterial Ischemic Stroke: Results of the VIPS II Study.Journal of the American Heart Association · 2025Article
- Abducens-nerve palsy with ipsilateral herpes zoster ophthalmicus and skin rash: a case report.International journal of ophthalmology · 2025Article
- Diagnostic value of anti-VZV IgG in neurological diseases among varicella unvaccinated individuals.Journal of neurovirology · 2024Article
- Association between Serum Varicella-Zoster Virus IgM and IgG and Prognosis of Ramsay Hunt Syndrome.Journal of clinical medicine · 2023Article
- Early Diagnosis of Herpes Zoster Neuralgia: A Narrative Review.Pain and therapy · 2023Review
- Review
- Diagnostic Usefulness of Varicella Zoster Virus-Specific Immunoglobulin (Ig) A and IgG in Patients With Herpes Zoster.Journal of Korean medical science · 2023Article
- Clinical features of varicella-zoster virus caused neurological diseases detected by metagenomic next-generation sequencing.Open medicine (Warsaw, Poland) · 2023Article
- Varicella-zoster virus in actively spreading segmental vitiligo skin: Pathological, immunochemical, and ultrastructural findings (a first and preliminary study).Pigment cell & melanoma research · 2023Article
- Atypical Varicella-Zoster Virus Reactivation: A Case Report.European journal of case reports in internal medicine · 2023Article
- Detection of Circulating VZV-Glycoprotein E-Specific Antibodies by Chemiluminescent Immunoassay (CLIA) for Varicella-Zoster Diagnosis.Pathogens (Basel, Switzerland) · 2022Article
- Herpes Zoster in an Immunocompetent Child without a History of Varicella.Pediatric reports · 2021Article
- Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus.Journal of neurovirology · 2020Article
- Hypovitaminosis Din Postherpetic Neuralgia-High Prevalence and Inverse Association with Pain: A Retrospective Study.Nutrients · 2019Article
- Varicella Zoster Virus Vasculitis and Adult Cerebrovascular Disease.The Neurohospitalist · 2019Review
- Analysis of sero-epidemiological characteristics of varicella in healthy children in Jiangsu Province, China.BMC infectious diseases · 2018Article
- Diagnostic Testing of Neurologic Infections.Neurologic clinics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratory tests for herpes zoster (HZ) are required to confirm varicella zoster virus (VZV) infection, especially when a skin lesion is not typical or apparent. The serological test for VZV IgM antibody is simple and cost-effective; however, the change in the VZV IgM-positive rate over the time course of the disease has not been investigated. Therefore, we conducted an observational study to evaluate the positive rate of VZV IgM results during the time course of HZ and estimate the VZV IgM-positive period.After obtaining serum from patients with typical HZ, the VZV IgM titer was examined using enzyme-linked immunosorbent assay methods. After logarithmic transformation of the VZV IgM titer and the period after the onset of HZ, regression analysis was performed with the 2 transformed variables.A total of 62 patients were included in this study, and VZV IgM antibody was positive only in 23 patients (37%). The estimated antibody-positive period after HZ onset was 3.5 weeks (95% confidence interval 2.8-4.6 weeks).These findings suggest that the serological diagnosis of VZV IgM to confirm HZ is only useful within 3.5 weeks after the onset of symptoms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.