Evidence map›Paper›PMID 27537194›Full record

ArticleNPJ primary care respiratory medicine2016

Asthma prescribing, ethnicity and risk of hospital admission: an analysis of 35,864 linked primary and secondary care records in East London.

Sally A Hull, Shauna McKibben, Kate Homer, Stephanie Jc Taylor, Katy Pike, Chris Griffiths

Abstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  12. Asthma: effect of excess short-acting βThe British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  13. Post-hospitalisation asthma management in primary care: a retrospective cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
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  15. Article
  16. Review
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  19. Short-acting βNPJ primary care respiratory medicine · 2022
    Article
  20. Reducing short-acting beta-agonist overprescribing in asthma: lessons from a quality-improvement prescribing project in East London.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sally A HullClinical Effectiveness Group, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK.
Shauna McKibbenAsthma UK Centre for Applied Research, Queen Mary University of London, London, UK.
Kate HomerClinical Effectiveness Group, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK.
Stephanie Jc TaylorAsthma UK Centre for Applied Research, Queen Mary University of London, London, UK.
Katy PikeRespiratory Critical Care and Anaesthesia Section, University College London, Institute of Child Health, London, UK.ORCID 0000-0003-4911-6082
Chris GriffithsAsthma UK Centre for Applied Research, Queen Mary University of London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inappropriate prescribing in primary care was implicated in nearly half of asthma deaths reviewed in the UK's recent National Review of Asthma Deaths. Using anonymised EMIS-Web data for 139 ethnically diverse general practices (total population 942,511) extracted from the North and East London Commissioning Support Unit, which holds hospital Secondary Uses Services (SUS)-linked data, we examined the prevalence of over-prescribing of short-acting β2-agonist inhalers (SABA), under-prescribing of inhaled corticosteroid (ICS) inhalers and solo prescribing of long-acting β2-agonists (LABA) to assess the risk of hospitalisation for people with asthma for 1 year ending August 2015. In a total asthma population of 35,864, multivariate analyses in adults showed that the risk of admission increased with greater prescription of SABA inhalers above a baseline of 1-3 (4-12 SABA: odds ratio (OR) 1.71; 95% confidence interval (CI) 1.20-2.46, ⩾13 SABA: OR 3.22; 95% CI 2.04-5.07) with increasing British Thoracic Society step (Step 3: OR 2.90; 95% CI 1.79-4.69, Step 4/5: OR 9.42; 95% CI 5.27-16.84), and among Black (OR 2.30; 95% CI 1.64-3.23) and south Asian adult populations (OR 1.83; 95% CI 1.36-2.47). Results in children were similar, but risk of hospitalisation was not related to ethnic group. There is a progressive risk of hospital admission associated with the prescription of more than three SABA inhalers a year. Adults (but not children) from Black and South Asian groups are at an increased risk of admission. Further work is needed to target care for these at-risk groups.

Indexed as

AdolescentAdultAgedAnti-Asthmatic AgentsAsthmaChildChild, PreschoolEthnicityHospitalizationHumansInappropriate PrescribingLondonMaleMiddle AgedPractice Patterns, Physicians'Primary Health CareAnti-Asthmatic Agents

Identifiers

PMID27537194
PMCPMC4989925

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.