Evidence map›Paper›PMID 27537054›Full record

ReviewInflammatory bowel diseases2016

Inflammatory Bowel Disease: Influence and Implications in Reproduction.

Louise E Glover, Blair Fennimore, Mary Wingfield

Open access · bronzeAbstract readReview
In one paragraph

Review in Inflammatory bowel diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Inflammatory bowel disease in pregnancy and breastfeeding.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  3. Impact of Obesity on Inflammatory Bowel Disease.Current gastroenterology reports · 2022
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Louise E Glover*Mucosal Inflammation Program, University of Colorado, Anschutz Medical Campus, Aurora, Colorado; †Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, Colorado; and ‡Merrion Fertility Clinic (MFC), National Maternity Hospital and Department of Obstetrics and Gynaecology, University College Dublin, Dublin, Ireland.
Blair Fennimore
Mary Wingfield
University of Colorado Anschutz Medical Campus · USMerrion Fertility Clinic · IE

Funding

METABOLIC CONTROL OF EPITHELIAL AUTOPHAGY DURING INFLAMMATIONR01DK103712 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 2015 to 2019
$1.7M
NIDDK NIH HHS R01 DK103712
6 · The paper itself

Abstract

The incidence and prevalence of inflammatory bowel disease (IBD) continues to rise with time, signifying its emergence as a global disease. Clinical onset of IBD, comprising Crohn's disease and ulcerative colitis, typically occurs before or at peak reproductive age. Although active disease in female patients is associated with reduced fertility and adverse obstetric outcomes in pregnancy, the molecular mechanisms underlying this altered reproductive course, and its impact on IBD transmission to offspring, remain poorly understood. Clinical and experimental studies have now begun to elucidate the hormonal, environmental, and microbial factors that modulate immune-reproductive cross talk in IBD and define their impact on maternal health, fetal development, and heritability of disease risk. Evolving insight into maternal-fetal imprinting in IBD has important implications for patient counseling and disease management during pregnancy and may help predict clinical outcomes for both mother and child.

Indexed as

FemaleHumansInflammatory Bowel DiseasesPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsReproduction

Identifiers

PMID27537054
PMCPMC5069142
OpenAlexW2514214259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.