ArticlePloS one2016
Corneal Higher Order Aberrations in Granular, Lattice and Macular Corneal Dystrophies.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Comparative analysis of higher-order aberration profiles in macular and granular corneal dystrophies.International ophthalmology · 2026Article
- Anterior Segment Optical Coherence Tomography in the Diagnosis of Corneal Stromal Dystrophies in Romania.Maedica · 2025Review
- Corneal higher-order aberrations in corneal endothelial decompensation secondary to obstetric forceps injury.Scientific reports · 2023Article
- Changes in corneal higher-order aberrations during treatment for infectious keratitis.Scientific reports · 2023Article
- Corneal irregularity and visual function using anterior segment optical coherence tomography in TGFBI corneal dystrophy.Scientific reports · 2022Article
- Detailed corneal and genetic characteristics of a pediatric patient with macular corneal dystrophy - case report.BMC ophthalmology · 2021Article
- Corneal higher-order aberrations in phlyctenular keratitis.Japanese journal of ophthalmology · 2020Article
- Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results.PloS one · 2020Article
- Inter-Ocular Asymmetry in Anterior Corneal Aberrations Using Placido Disk-Based Topography.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Corneal topometric, aberrometric and biomechanical parameters in mucopolysaccharidosis patients.PloS one · 2019Article
- A comparative study: deep anterior lamellar keratoplasty for corneal dystrophies using two different donor stromal tissues.International ophthalmology · 2018Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the corneal higher-order aberrations (HOAs) in granular, lattice and macular corneal dystrophies.
methodsThis retrospective study includes consecutive patients who were diagnosed as granular corneal dystrophy type2 (GCD2; 121 eyes), lattice corneal dystrophies type 1, type 3A (LCDI; 20 eyes, LCDIIIA; 32 eyes) and macular corneal dystrophies (MCD; 13 eyes), and 18 healthy control eyes. Corneal HOAs were calculated using anterior segment optical coherence tomography, and the correlations between HOAs and visual acuity were analyzed.
resultsHOAs of the total cornea within 4 mm diameter were significantly larger in GCD2 (0.17 ± 0.35 μm), in LCDI (0.33 ± 0.27), LCDIIIA (0.61 ± 1.56) and in MCD (0.23 ± 0.18), compared with healthy controls (0.09 ± 0.02μm, all P < 0.01). HOAs of the total cornea within 6 mm diameter were significantly larger in GCD2 (0.32 ± 0.48), in LCDI (0.60 ± 0.46), LCDIIIA (0.83 ± 2.29) and in MCD (0.44 ± 0.24), compared with healthy controls (0.19 ± 0.06, all P < 0.001). In GCD2, there was no significant correlation between logMAR and HOAs (r = 0.113, P = 0.227). In MCD, LCDI and LCDIIIA, logMAR was positively significantly correlated with HOAs (r = 0.620 and P = 0.028, r = 0.587 and P = 0.007, r = 0.614 and P < 0.001, respectively).
conclusionsIncreased HOAs occur in eyes with corneal dystrophies, especially in eye with LCD and MCD. Larger amount corneal HOAs are associated with poorer visual acuity in patients with LCD and MCD.
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