Evidence map›Paper›PMID 27536741›Full record

ArticleThe Analyst2016

Novel carbon-fiber microelectrode batch fabrication using a 3D-printed mold and polyimide resin.

Elefterios Trikantzopoulos, Cheng Yang, Mallikarjunarao Ganesana, Ying Wang, B Jill Venton

Abstract read
In one paragraph

Article in The Analyst, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. High Performance, Low Cost Carbon Nanotube Yarn based 3D Printed Electrodes Compatible with a Conventional Screen Printed Electrode System.... IEEE International Symposium on Medical Measurements and Applications : proceedings. IEEE International Symposium on Medical Measurements and Applications · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elefterios Trikantzopoulos *Department of Chemistry, University of Virginia, Charlottesville, VA 22904.
Cheng Yang *Department of Chemistry, University of Virginia, Charlottesville, VA 22904.
Mallikarjunarao GanesanaDepartment of Chemistry, University of Virginia, Charlottesville, VA 22904.
Ying WangDepartment of Chemistry, University of Virginia, Charlottesville, VA 22904.
B Jill VentonDepartment of Chemistry, University of Virginia, Charlottesville, VA 22904.

Funding

Mechanism and function of transient adenosine signaling in the brainR01NS076875 · NINDS · UNIVERSITY OF VIRGINIA · PI VENTON, B. JILL · 2012 to 2016
$1.6M
Carbon nanotube fiber and yarn microelectrodes for high temporal resolution measuR21DA037584 · NIDA · UNIVERSITY OF VIRGINIA · PI VENTON, B. JILL · 2014 to 2015
$413k
NIDA NIH HHS R21 DA037584NINDS NIH HHS R01 NS076875
6 · The paper itself

Abstract

Glass insulated carbon-fiber microelectrodes (CFMEs) are standard tools for the measurement of neurotransmitters. However, electrodes are fabricated individually and the glass can shatter, limiting application in higher order mammals. Here, we developed a novel microelectrode batch fabrication method using a 3D-printed mold and polyimide resin insulating agent. The 3D-printed mold is low cost, customizable to change the electrode shape, and allows 40 electrodes to be made simultaneously. The polyimide resin is biocompatible, quick to cure, and does not adhere to the plastic mold. The electrodes were tested for the response to dopamine with fast-scan cyclic voltammetry both in vitro and in vivo and performed similarly to traditional glass-insulated electrodes, but with lower background currents. Thus, polyimide-insulated electrodes can be mass-produced using a 3D-printed mold and are an attractive alternative for making cheap, biocompatible microelectrodes.

Indexed as

CarbonMicroelectrodesResins, SyntheticAnimalsDopamineMaleRatsRats, Sprague-DawleyCarbonDopaminepolyimide resinResins, Synthetic

Identifiers

PMID27536741
PMCPMC5019535

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.