Evidence map›Paper›PMID 27536732›Full record

ArticleJCI insight2016

Rana Rais, Weiwei Jiang, Huihong Zhai, Krystyna M Wozniak, Marigo Stathis, Kristen R Hollinger, Ajit G Thomas, Camilo Rojas, James J Vornov, Michael Marohn and 2 more

Open access · goldAbstract read
In one paragraph

Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Immunometabolic chaos in septic shock.Journal of leukocyte biology · 2025
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  10. Targeting glutamate carboxypeptidase II in IBD.Advances in pharmacology (San Diego, Calif.) · 2024
    Review
  11. Article
  12. Review
  13. PSMA-Targeted PET Radiotracer [Clinical and experimental gastroenterology · 2023
    Article
  14. Article
  15. Article
  16. Multiomic Analysis of the Gut Microbiome in Psoriasis Reveals Distinct Host‒Microbe Associations.JID innovations : skin science from molecules to population health · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Rana RaisDepartment of Neurology, Baltimore, Maryland, USA; Johns Hopkins Drug Discovery, Baltimore, Maryland, USA.
Weiwei JiangDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huihong ZhaiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Krystyna M WozniakJohns Hopkins Drug Discovery, Baltimore, Maryland, USA.
Marigo StathisJohns Hopkins Drug Discovery, Baltimore, Maryland, USA.
Kristen R HollingerDepartment of Neurology, Baltimore, Maryland, USA; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ajit G ThomasJohns Hopkins Drug Discovery, Baltimore, Maryland, USA.
Camilo RojasJohns Hopkins Drug Discovery, Baltimore, Maryland, USA; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
James J VornovMedpace, Cincinnati, Ohio, USA.
Michael MarohnDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Xuhang LiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Barbara S SlusherDepartment of Neurology, Baltimore, Maryland, USA; Johns Hopkins Drug Discovery, Baltimore, Maryland, USA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Drug Discovery Laboratory (Norway) · NOJohns Hopkins Medicine · USJohns Hopkins University · USMedpace (United States) · USUnion Hospital · CN

Funding

Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
GCPII Inihibitors for the treatment of chemotherapy-induced neuropathyR01CA161056 · NCI · JOHNS HOPKINS UNIVERSITY · PI SLUSHER, BARBARA STAUCH · 2012 to 2016
$1.8M
NCI NIH HHS R01 CA161056NIDDK NIH HHS P30 DK089502
6 · The paper itself

Abstract

Recent gene-profiling analyses showed significant upregulation of the folate hydrolase (

Identifiers

PMID27536732
PMCPMC4985244
OpenAlexW2492288257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.