ArticleRespiratory medicine case reports2016
Two cases of pleuroparenchymal fibroelastosis diagnosed with transbronchial lung biopsy.
Article in Respiratory medicine case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Korean Guidelines for the Diagnosis and Management of Interstitial Lung Disease: Other Forms of Interstitial Lung Disease.Tuberculosis and respiratory diseases · 2025Article
- Pleuroparenchymal Fibroelastosis: A Review with a Focus on a Non-Infectious Complications after Hematopoietic Stem Cell Transplant.Biomedicines · 2023Review
- Nintedanib in idiopathic and secondary pleuroparenchymal fibroelastosis.Orphanet journal of rare diseases · 2021Article
- Transbronchial cryobiopsy for diagnosis of pleuroparenchymal fibroelastosis.Respiratory medicine case reports · 2020Article
- Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.Annals of the American Thoracic Society · 2019Review
- Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features.Internal medicine (Tokyo, Japan) · 2019Article
- Pleuroparenchymal fibroelastosis with positive MPO-ANCA diagnosed with a CT-guided percutaneous needle biopsy.BMJ case reports · 2018Article
- Pleuroparenchymal fibroelastosis presenting with pneumothorax.SAGE open medical case reports · 2018Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare subset of idiopathic interstitial pneumonias (IIPs). Here we present two patients with PPFE in which the histology was confirmed with transbronchial lung biopsy (TBLB). The 25-year-old and 64-year-old men were both slender with a long history of pulmonary upper lobe fibrosis and a marked restrictive impairment. Although the imaging findings supported the diagnosis of PPFE, surgical lung biopsy (SLB) seemed to be needed to identify fibroelastosis for the definite diagnosis. However, we selected TBLB instead of SLB because of their general condition and the risk such as prolonged pneumothorax after TBLB. TBLB specimens in both patients showed aggregates of elastic fibers in the submucosa that were essential clues for the histological diagnosis of PPFE. TBLB may be an alternative tool for the histological diagnosis of PPFE, although a multidisciplinary discussion is necessary for the final diagnosis of PPFE as a clinicopathological entity.
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