Evidence map›Paper›PMID 27536540›Full record

ArticleSpringerPlus2016

Analysis of oral yeast microflora in patients with oral squamous cell carcinoma.

Csaba Berkovits, Adél Tóth, Judit Szenzenstein, Tünde Deák, Edit Urbán, Attila Gácser, Katalin Nagy

Abstract read
In one paragraph

Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Human Microbiome in Relation to Cancer Risk: A Systematic Review of Epidemiologic Studies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Pooled it
  2. Frontiers in cellular and infection microbiology · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Alterations of the Oral Microbiota Profiles in Chinese Patient With Oral Cancer.Frontiers in cellular and infection microbiology · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. A dysbiotic mycobiome dominated byJournal of oral microbiology · 2017
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Csaba BerkovitsDepartment of Oral Surgery, University of Szeged, Tisza Lajos krt. 64, Szeged, 6720 Hungary.
Adél TóthDepartment of Microbiology, University of Szeged, Közép fasor 52, Szeged, 6726 Hungary.
Judit SzenzensteinDepartment of Microbiology, University of Szeged, Közép fasor 52, Szeged, 6726 Hungary.
Tünde DeákInstitute of Clinical Microbiology, University of Szeged, Semmelweis u. 6, Szeged, 6725 Hungary.
Edit UrbánInstitute of Clinical Microbiology, University of Szeged, Semmelweis u. 6, Szeged, 6725 Hungary.
Attila Gácser *Department of Microbiology, University of Szeged, Közép fasor 52, Szeged, 6726 Hungary.
Katalin Nagy *Department of Oral Surgery, University of Szeged, Tisza Lajos krt. 64, Szeged, 6720 Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral squamous cell carcinoma (OSCC) is the most common form of oral cancer, in this study, the association between OSCC and oral yeast carriage was investigated.

findings20 patients having OSCC as well as 40 healthy controls were tested for the presence of yeasts in the oral cavity. Fungal burdens were examined by colony forming unit determinations, while the different yeast genera in patient samples were identified by matrix-associated laser desorption/ionization-time of flight-mass spectrometry. We found that the level of oral yeast carriage was significantly higher in patients with OSCC that was accompanied by a higher diversity of yeasts in the oral cavity of these patients. We also examined the extracellular enzyme production of isolated Candida spp.; however, we found that there was no association between the lipase/protease producing capacity of Candida strains and the higher colonisation rate of neoplastic epithelium.

conclusionsIn conclusion, our results corroborate the findings of previous studies regarding the association between oral yeast carriage and epithelial carcinoma.

Indexed as

CandidaMALDI-TOFOral squamous cell carcinomaYeast

Identifiers

PMID27536540
PMCPMC4974209

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.