Crystal structure of 2-isopropyl-5,7'-dimethyl-1',3',3a',6',8a',8b'-hexa-hydro-spiro-[cyclo-hexane-1,6'-furo[3,4-d]imidazo[1,5-b]isoxazol]-8'(7'H)-one.

Heithem Abda, Khaireddine Ezzayani, Kaiss Aouadi, Taha Guerfel, Sebastien Vidal, Moncef Msaddek

Abstract read

In one paragraph

Article in Acta crystallographica. Section E, Crystallographic communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heithem AbdaUniversity of Monastir, Heterocyclic Chemistry Laboratory, Products, Natural and Reactivity, Faculty of Sciences of Monastir, Avenue of the Environment, 5000 Monastir, Tunisia.

Khaireddine EzzayaniUniversity of Monastir, Laboratory of Physical Chemistry of Materials, Faculty of Sciences of Monastir, Avenue of the Environment, 5019 Monastir, Tunisia.

Kaiss AouadiUniversity of Monastir, Heterocyclic Chemistry Laboratory, Products, Natural and Reactivity, Faculty of Sciences of Monastir, Avenue of the Environment, 5000 Monastir, Tunisia.

Taha GuerfelLaboratory of Electrochemistry, Materials and Environment, Kairouan University, 3100 Kairouan, Tunisia.

Sebastien VidalUniversity of Lyon CNRS, Institute of Chemistry and Biochemistry and Molecular Supramolecular, UMR 5246, Laboratoire de Chimie Organique 2-Glycochemistry, Curien Building, 43 Boulevard du 11 Novembre 1918, F-69622 Villeurbanne, France.

Moncef MsaddekUniversity of Monastir, Heterocyclic Chemistry Laboratory, Products, Natural and Reactivity, Faculty of Sciences of Monastir, Avenue of the Environment, 5000 Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the title compound, C17H28N2O3, the isoxazolidine ring adopts an envelope conformation with the O atom deviating from the mean plane of the other four ring atoms by 0.617 (1) Å. In the crystal, mol-ecules are linked via weak C-H⋯O hydrogen bonds, forming chains which extend along the b-axis direction.

Indexed as

crystal structurehydrogen bondingisoxazolidine

Identifiers

PMID27536401

DOI10.1107/S2056989016010641

PMCPMC4971860

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.