ArticleJournal of dentistry (Tehran, Iran)2016
Effect of Fixed Orthodontic Treatment on Salivary Flow, pH and Microbial Count.
Article in Journal of dentistry (Tehran, Iran), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397871 (Changes in Salivary Parameters in Patients Undergoing Clear Aligner Orthodontic Treatment), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Salivary Parameters in Patients Undergoing Clear Aligner Orthodontic Treatment: A Randomized Controlled Trial
Who cites it
30 citing papers in PubMed.
- Salivary pH changes under the effect of stainless steel versus elastomeric ligatures in fixed orthodontic patients: a single-center, randomized controlled clinical trial.BMC oral health · 2021Trial
- Salivary Cobalt, Nickel, Chromium and Titanium After Fixed Orthodontic Appliance Removal: A 3-Month Pilot Longitudinal Study.Dentistry journal · 2026Article
- Microbial and periodontal shifts induced by orthodontic appliances: a comparative clinical study.Acta odontologica Scandinavica · 2026Article
- Assessment and Evaluation of Oral Health in Orthodontic Patients: A Cross-Sectional Study.Cureus · 2025Article
- Bacterial Colonization of Orthodontic Devices (Molar Bands, Nance Buttons, and Acrylic Plates) and Its Impact on the Marginal Periodontium and Palatal Fibromucosa in Teenagers: A Cross-Sectional Clinical-Microbiological Study.Medicina (Kaunas, Lithuania) · 2025Article
- Strategic sequencing of orthodontic treatment and periodontal regenerative surgery: A literature review.Journal of dental sciences · 2025Review
- Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances.iScience · 2024Review
- Tongue microbiota in relation to the breathing preference in children undergoing orthodontic treatment.BMC oral health · 2024Article
- Analysis of the Effects of Different Orthodontic Appliances on Salivary pH Levels: AnJournal of pharmacy & bioallied sciences · 2024Article
- Conformation Effect on the Mechanical and Microbiological Behavior of Invisible Orthodontic Aligners.Materials (Basel, Switzerland) · 2024Article
- Effect of adding arginine at different concentrations to experimental orthodontic resins: an in vitro study.Brazilian oral research · 2024Article
- A Retrospective Histological Study on Palatal and Gingival Mucosa Changes during a Rapid Palatal Expansion Procedure.Biomedicines · 2023Article
- Changes in the pH and the Flow Rate of Saliva During Orthodontic Treatment with Fixed Orthodontic Appliances: A Systematic Review.Turkish journal of orthodontics · 2023Article
- An assessment of the pH changes and metal ions released into artificial saliva by fake orthodontic braces.BMC oral health · 2023Article
- SalivaryActa odontologica latinoamericana : AOL · 2022Article
- Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study.BMC oral health · 2022Article
- Screening of biochemical parameters in the orthodontic treatment with the fixed appliances: A follow-up study.Saudi journal of biological sciences · 2021Article
- What Are the Cleaning and Disinfection Methods for Acrylic Orthodontic Removable Appliance? A Systematic Review.Children (Basel, Switzerland) · 2021Review
- Physiological and Immunological Changes Associated with Oral Microbiota When Using a Thermoplastic Retainer.Molecules (Basel, Switzerland) · 2021Article
- Prioritization of predisposing factors of gingival hyperplasia during orthodontic treatment: the role of amount of biofilm.BMC oral health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe present study was designed to evaluate the changes in saliva properties and oral microbial flora in patients undergoing fixed orthodontic treatment. MATERIALS AND
methodsTwo important saliva properties namely the salivary flow rate and pH as well as oral microbial flora were assessed in 30 orthodontic patients before starting fixed orthodontic treatment and after six, 12 and 18 weeks of treatment. Selective media, Sabouraud dextrose agar, Mitis salivarius agar and Rogosa agar were used for isolation of Candida albicans, Streptococcus mutans and Lactobacillus acidophilus, respectively. Statistical analysis was performed using Friedman and Dunn's tests. P< 0.05 was considered statistically significant.
resultsAfter six, 12 and 18 weeks of commencing fixed orthodontic treatment, the total colony counts of Candida albicans, Streptococcus mutans and Lactobacillus acidophilus showed a significant increase. The saliva pH decreased during the orthodontic treatment (P< 0.05) while the salivary flow did not change significantly.
conclusionsFixed orthodontic treatment causes major changes in the saliva properties. The changes in oral microflora and saliva properties show the importance of caries preventive measures during orthodontic treatment.
Indexed as
Identifiers
27536324PMC4983561What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.