ArticleCurrent oncology (Toronto, Ont.)2016
Is clinical breast examination important for breast cancer detection?
Article in Current oncology (Toronto, Ont.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07023198 (Provider-Initiated Screening Clinical Breast Examination and Patient Navigation in Sub-Saharan Africa), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Provider-Initiated Screening Clinical Breast Examination and Patient Navigation in Sub-Saharan Africa
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Pooled it
- Trial
- Association of Pre-Diagnosis Breast Assessment Practices and Risk Factors with Breast Cancer Stage at Diagnosis: A Single-Center Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Inhibitory Effect of Progesterone on Breast Cancer Progression and Migration via the Regulation of Epithelial-Mesenchymal Transition.Oncology research · 2026Article
- The Rise and Refinement of Breast Thread Lifting: A Contemporary Review.Journal of clinical medicine · 2025Review
- Factors influencing clinical breast cancer screening: A cross-sectional study among Islamic women in Kumasi Metropolis of Ghana.PloS one · 2025Article
- Clicks and checks: investigating the association between internet usage frequency and women's uptake of clinical breast examination in Ghana.BMC health services research · 2024Article
- Targeting the Oxytocin Receptor for Breast Cancer Management: A Niche for Peptide Tracers.Journal of medicinal chemistry · 2024Review
- Factors associated with uptake of breast and cervical cancer screening among Nepalese women: Evidence from Nepal Demographic and Health Survey 2022.PLOS global public health · 2024Article
- Determinants of breast cancer screening among women of reproductive age in sub-Saharan Africa: A multilevel analysis.PloS one · 2024Article
- Clinical breast examination and its associated factors among reproductive age women in Ghana: multilevel logistic regression analysis.Frontiers in oncology · 2024Article
- The prevalence and predictors of clinical breast cancer screening in Sub-Saharan African countries: a multilevel analysis of Demographic Health Survey.Frontiers in public health · 2024Article
- The Influence of Screening Mammography Cessation and Resumption on Breast Cancer Presentation and Treatment: A Multi-Hospital Health System Experience During the Early COVID-19 Pandemic.European journal of breast health · 2022Article
- The Efficacy of Clinical Breast Exams and Breast Self-Exams in Detecting Malignancy or Positive Ultrasound Findings.Cureus · 2022Article
- Practice of breast self-examination and associated factors among female health professionals working in public hospitals of Harari regional state: Eastern Ethiopia multicenter study.Frontiers in oncology · 2022Article
- Evaluation of breast stiffness pathology based on breast compression during mammography: Proposal for novel breast stiffness scale classification.Clinics (Sao Paulo, Brazil) · 2022Article
- Knowledge and Practices of Female Nurses at Primary Health Care Clinics in Gaza Strip-Palestine Regarding Early Detection of Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Practical Utility of Diagnostic Clinical Breast Examination in the Diagnosis of Breast Cancer.Cureus · 2021Article
- Bilateral mammary hibernoma mimicking breast carcinoma: a diagnostic challenge.BMJ case reports · 2021Article
- Breast health screening: a UK-wide questionnaire.BMJ nutrition, prevention & health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundScreening clinical breast examination (cbe) is controversial; the use of cbe is declining not only as a screening tool, but also as a diagnostic tool. In the present study, we aimed to assess the value of cbe in breast cancer detection in a tertiary care centre for breast diseases.
methodsThis retrospective study of all breast cancers diagnosed between July 1999 and December 2010 at our centre categorized cases according to the mean of detection (cbe, mammography, or both). A cbe was considered "abnormal" in the presence of a mass, nipple discharge, skin or nipple retraction, edema, erythema, peau d'orange, or ulcers.
resultsDuring the study period, a complete dataset was available for 6333 treated primary breast cancers. Cancer types were ductal carcinoma in situ (15.3%), invasive ductal carcinoma (75.7%), invasive lobular carcinoma (9.0%), or others (2.2%). Of the 6333 cancers, 36.5% (n = 2312) were detected by mammography alone, 54.8% (n = 3470) by mammography and cbe, and 8.7% (n = 551) by physician-performed cbe alone (or 5.3% if considering ultrasonography). Invasive tumours diagnosed by cbe alone were more often triple-negative, her2-positive, node-positive, and larger than those diagnosed by mammography alone (p < 0.05).
conclusionsA significant number of cancers would have been missed if cbe had not been performed. Compared with cancers detected by mammography alone, those detected by cbe had more aggressive features. Clinical breast examination is a very low-cost test that could improve the detection of breast cancer and could prompt breast ultrasonography in the case of a negative mammogram.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.