Evidence map›Paper›PMID 27535735›Full record

ArticleBMJ case reports2016

HELLP syndrome: a diagnostic conundrum with severe complications.

Devika Rao, Nikulkumar Kumar Chaudhari, Robert Michael Moore, Belinda Jim

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Devika RaoDepartment of Medicine, Jacobi Medical Center, Bronx, New York, USA.
Nikulkumar Kumar ChaudhariDepartment of Medicine/Nephrology, Jacobi Medical Center, Bronx, New York, USA.
Robert Michael MooreJacobi Medical Center, Bronx, New York, USA.
Belinda JimDepartment of Medicine, Jacobi Medical Center, Bronx, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HELLP (haemolysis, elevated liver enzymes, low platelets) syndrome is believed to be part of the spectrum of pre-eclampsia, which falls within the category of hypertensive disorders of pregnancy. Maternal and fetal complications are more severe in HELLP as opposed to pre-eclampsia alone. We describe a 26-year-old primigravida woman with no medical history who presents with signs of HELLP with marked transaminitis and mild disseminated intravascular coagulation at 35 weeks of gestation who required emergent delivery of the fetus; the patient also sustained acute kidney injury requiring continuous veno-venous hemodiafiltration and a prolonged intensive care unit admission. Remarkably, with supportive care, all laboratory derangements, including renal function, normalised after 4 weeks. We discuss the diagnostic conundrum when faced with the possible diagnosis of HELLP in discriminating from its many imitators in order to assume proper treatment.

Indexed as

Abdominal PainAdultCesarean SectionCritical CareDiagnosis, DifferentialFemaleHELLP SyndromeHumansPregnancyPregnancy OutcomePrenatal CarePrenatal DiagnosisTreatment OutcomeTriage

Identifiers

PMID27535735
PMCPMC5015173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.