Evidence map›Paper›PMID 27535401›Full record

ReviewUpdates in surgery2016

Role of local ablative techniques (Radiofrequency ablation and Irreversible Electroporation) in the treatment of pancreatic cancer.

Salvatore Paiella, Roberto Salvia, Roberto Girelli, Isabella Frigerio, Alessandro Giardino, Mirko D'Onofrio, Giulia De Marchi, Claudio Bassi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Updates in surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Preclinical Study of Biphasic Asymmetric Pulsed Field Ablation.Frontiers in cardiovascular medicine · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Salvatore PaiellaGeneral and Pancreatic Surgery Department, The Pancreas Institute, University of Verona Hospital Trust, Piazzale L.A. Scuro 10, 37134, Verona, Italy.
Roberto SalviaGeneral and Pancreatic Surgery Department, The Pancreas Institute, University of Verona Hospital Trust, Piazzale L.A. Scuro 10, 37134, Verona, Italy.
Roberto GirelliPancreatic Surgical Unit, Casa di Cura Pederzoli, Peschiera Del Garda, Verona, Italy.
Isabella FrigerioPancreatic Surgical Unit, Casa di Cura Pederzoli, Peschiera Del Garda, Verona, Italy.
Alessandro GiardinoPancreatic Surgical Unit, Casa di Cura Pederzoli, Peschiera Del Garda, Verona, Italy.
Mirko D'OnofrioRadiology Department, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Giulia De MarchiGastroenterology B Department, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Claudio BassiGeneral and Pancreatic Surgery Department, The Pancreas Institute, University of Verona Hospital Trust, Piazzale L.A. Scuro 10, 37134, Verona, Italy. Claudio.bassi@univr.it.
University of Verona · ITCasa di Cura Villa Garda · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thanks to continuous research and investment in technology, the ablation of tumors has become common. Through the application of different types of energy is possible to induce cellular injury of the neoplastic tissue, leading to cellular death. Radiofrequency ablation (RFA) and irreversible electroporation (IRE) represent the most applied ablative techniques on pancreatic cancer. RFA and IRE, causing necrosis and apoptosis of neoplastic cells, are able to destroy neoplastic tissue, to drastically modify the neoplastic microenvironment and, possibly, to stimulate both directly and indirectly the anti-tumor immune system. This article provides part of our experience with the application of RFA and IRE on pancreatic adenocarcinoma (PDAC).

Indexed as

AdenocarcinomaCatheter AblationElectroporationHumansPancreatectomyPancreatic NeoplasmsTreatment OutcomeAblative techniquesIrreversible electroporationLocally advanced pancreatic adenocarcinomaPancreatic carcinomaRadiofrequency ablation

Identifiers

PMID27535401
OpenAlexW2518374037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.