Evidence map›Paper›PMID 27535226›Full record

ArticleThe Journal of biological chemistry2016

Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells.

Javier Ávila-Medina, Eva Calderón-Sánchez, Patricia González-Rodríguez, Francisco Monje-Quiroga, Juan Antonio Rosado, Antonio Castellano, Antonio Ordóñez, Tarik Smani

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Orai storeoperated CaChannels (Austin, Tex.) · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. RNA sequencing least shrew (Frontiers in genetics · 2023
    Article
  9. Article
  10. Role of store-operated Ca2+ entry in cardiovascular disease.Cell communication and signaling : CCS · 2022
    Review
  11. Article
  12. Article
  13. ORAI1 CaFrontiers in cell and developmental biology · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. TRPC and TRPV Channels' Role in Vascular Remodeling and Disease.International journal of molecular sciences · 2020
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Javier Ávila-MedinaFrom the Departamento de Fisiología Médica y Biofísica and Groupo de Fisiopatología Cardiovascular, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Sevilla, Spain.
Eva Calderón-SánchezGroupo de Fisiopatología Cardiovascular, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Sevilla, Spain.
Patricia González-RodríguezFrom the Departamento de Fisiología Médica y Biofísica and.
Francisco Monje-Quirogathe Department of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Wien, Austria, and.
Juan Antonio Rosadothe Departamento de Fisiología, Universidad de Extremadura, 10071 Cáceres, Spain.
Antonio CastellanoFrom the Departamento de Fisiología Médica y Biofísica and.
Antonio OrdóñezGroupo de Fisiopatología Cardiovascular, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Sevilla, Spain.
Tarik SmaniFrom the Departamento de Fisiología Médica y Biofísica and Groupo de Fisiopatología Cardiovascular, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Sevilla, Spain, tasmani@us.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voltage-dependent Ca

Indexed as

AnimalsAortaCalciumCalcium Channels, L-TypeCalcium SignalingMiceMice, KnockoutMultiprotein ComplexesMuscle, Smooth, VascularMyocytes, Smooth MuscleORAI1 ProteinSerotoninTRPC Cation ChannelsVasoconstrictionCACNA1C protein, mouseCalciumCalcium Channels, L-TypeMultiprotein ComplexesORAI1 ProteinOrai1 protein, mouseSerotonintransient receptor potential cation channel, subfamily C, member 1TRPC Cation Channelscalciumcalcium release-activated calcium channel protein 1 (ORAI1)CaV1.2CaV1.2 channelexcitation-contraction coupling (E-C coupling)ion channelOrai1TRPC1vascular smooth muscle cellsVascular tone regulation

Identifiers

PMID27535226
PMCPMC5076523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.