Evidence map›Paper›PMID 27535146›Full record

ArticleDevelopment genes and evolution2016

Cell tracking supports secondary gastrulation in the moon jellyfish Aurelia.

David A Gold, Nagayasu Nakanishi, Nicholai M Hensley, Volker Hartenstein, David K Jacobs

Abstract read
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In one paragraph

Article in Development genes and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David A GoldDepartment of Ecology and Evolution, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Nagayasu NakanishiDepartment of Ecology and Evolution, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Nicholai M HensleyDepartment of Ecology and Evolution, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Volker HartensteinDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
David K JacobsDepartment of Ecology and Evolution, University of California, Los Angeles, Los Angeles, CA, 90095, USA. djacobs@ucla.edu.
University of California, Los Angeles · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The moon jellyfish Aurelia exhibits a dramatic reorganization of tissue during its metamorphosis from planula larva to polyp. There are currently two competing hypotheses regarding the fate of embryonic germ layers during this metamorphosis. In one scenario, the original endoderm undergoes apoptosis and is replaced by a secondary endoderm derived from ectodermal cells. In the second scenario, both ectoderm and endoderm remain intact through development. In this study, we performed a pulse-chase experiment to trace the fate of larval ectodermal cells. We observed that prior to metamorphosis, ectodermal cells that proliferated early in larval development concentrate at the future oral end of the polyp. During metamorphosis, these cells migrate into the endoderm, extending all the way to the aboral portion of the gut. We therefore reject the hypothesis that larval endoderm remains intact during metamorphosis and provide additional support for the "secondary gastrulation" hypothesis. Aurelia appears to offer the first and only described case where a cnidarian derives its endoderm twice during normal development, adding to a growing body of evidence that germ layers can be dramatically reorganized in cnidarian life cycles.

Indexed as

AnimalsCell MovementCell TrackingFemaleGastrulationLarvaScyphozoaAureliaCnidariaGastrulationMoon jellyfish

Identifiers

PMID27535146
OpenAlexW2510730256

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.