ArticleJournal of the Royal Society, Interface2016
Putting life on ice: bacteria that bind to frozen water.
Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 67 citations in OpenAlex.
- Microbial succession and hydrocarbon-degrading potential in Arctic sea ice exposed to dispersed crude oil and chemical dispersant.FEMS microbes · 2026Article
- Ice gliding diatoms establish record-low temperature limits for motility in a eukaryotic cell.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Glycopolypeptoids as Novel Biomimetic Antifreeze Agents: Structural Design, Synthesis, and Antifreeze Properties.Polymers · 2025Article
- Article
- From freezing to functioning: cellular strategies of cold-adapted bacteria for surviving in extreme environments.Archives of microbiology · 2024Review
- Article
- Domain structure and cross-linking in a giant adhesin from the Mobiluncus mulieris bacterium.Acta crystallographica. Section D, Structural biology · 2023Article
- A Review on Psychrophilic β-D-Galactosidases and Their Potential Applications.Applied biochemistry and biotechnology · 2023Review
- Comprehensive insights on environmental adaptation strategies in Antarctic bacteria and biotechnological applications of cold adapted molecules.Frontiers in microbiology · 2023Review
- Flavonoid-Decorated Nano-gold for Antimicrobial Therapy Against Gram-negative Bacteria Escherichia coli.Applied biochemistry and biotechnology · 2021Article
- Effect of pH on the activity of ice-binding protein from Marinomonas primoryensis.Extremophiles : life under extreme conditions · 2021Article
- Pigment production by cold-adapted bacteria and fungi: colorful tale of cryosphere with wide range applications.Extremophiles : life under extreme conditions · 2020Review
- Association of NovelFrontiers in microbiology · 2020Article
- Peptidic Antifreeze Materials: Prospects and Challenges.International journal of molecular sciences · 2019Review
- The physics and chemistry of ice.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2019Article
- Ice-binding proteins and the applicability and limitations of the kinetic pinning model.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2019Article
- Falling water ice affinity purification of ice-binding proteins.Scientific reports · 2018Article
- Balance between hydration enthalpy and entropy is important for ice binding surfaces in Antifreeze Proteins.Scientific reports · 2017Article
- Multiple ice-binding proteins of probable prokaryotic origin in an Antarctic lake alga, Chlamydomonas sp. ICE-MDV (Chlorophyceae).Journal of phycology · 2017Article
- Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice.Science advances · 2017Article
Corrections and comments
- Commented on by
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Ice-binding proteins (IBPs) are typically small, soluble proteins produced by cold-adapted organisms to help them avoid ice damage by either resisting or tolerating freezing. By contrast, the IBP of the Antarctic bacterium Marinomonas primoryensis is an extremely long, 1.5 MDa protein consisting of five different regions. The fourth region, a 34 kDa domain, is the only part that confers ice binding. Bioinformatic studies suggest that this IBP serves as an adhesin that attaches the bacteria to ice to keep it near the top of the water column, where oxygen and nutrients are available. Using temperature-controlled cells and a microfluidic apparatus, we show that M. primoryensis adheres to ice and is only released when melting occurs. Binding is dependent on the mobility of the bacterium and the functionality of the IBP domain. A polyclonal antibody raised against the IBP region blocks bacterial ice adhesion. This concept may be the basis for blocking biofilm formation in other bacteria, including pathogens. Currently, this IBP is the only known example of an adhesin that has evolved to bind ice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.