Evidence map›Paper›PMID 27534564›Full record

ArticleHead and neck pathology2017

Mucinous Carcinoma with Neuroendocrine Differentiation of Salivary Gland Origin.

Frankie K Wong, Zachary S Zumsteg, Claude-Jean Langevin, Nabilah Ali, Shawn Maclary, Bonnie L Balzer, Allen S Ho

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PubMed Full text at PMC Publisher
In one paragraph

Article in Head and neck pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Frankie K WongDepartment of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Rm. 5537, Los Angeles, CA, 90048, USA.
Zachary S ZumstegDepartment of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Los Angeles, CA, 90048, USA.
Claude-Jean LangevinDivision of Plastic and Reconstructive Surgery, Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Los Angeles, CA, 90048, USA.
Nabilah AliDepartment of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Rm. 5537, Los Angeles, CA, 90048, USA.
Shawn MaclaryDepartment of Pathology, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Los Angeles, CA, 90048, USA.
Bonnie L BalzerDepartment of Pathology, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Los Angeles, CA, 90048, USA.
Allen S HoDepartment of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Rm. 5537, Los Angeles, CA, 90048, USA. allen.ho@cshs.org.
Cedars-Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary mucinous adenocarcinomas of the salivary gland are rare malignancies defined by aggregates of epithelial cells suspended in large pools of extracellular mucin. We report a case of a giant mucinous adenocarcinoma of salivary gland origin, with low-grade cytoarchitectural features and neuroendocrine differentiation arising in the submental region. Grossly, the tumor measured 12.5 × 13.4 × 8.2 cm and replaced the bone and soft tissues of the anterior oral cavity. Microscopically, the neoplasm was composed of large extracellular pools of mucin, which contained papillary and acinar aggregates, and small nodules of ductal type epithelium with minimal nuclear enlargement, powdery chromatin and little pleomorphism. The nodules comprised 20 % of the tumor and showed morphologic and immunohistochemical evidence of neuroendocrine differentiation. Examination revealed histologic features comparable to mammary gland analogues in mucin predominance, ductal type morphology, expression of estrogen and progesterone receptors, and GATA-3 positivity. This is the first case reported of mucin-rich carcinoma of salivary gland origin exhibiting neuroendocrine differentiation.

Indexed as

Adenocarcinoma, MucinousHumansMaleMiddle AgedSalivary Gland NeoplasmsHead and neck cancerMucinous adenocarcinomaMucin-rich carcinomaNeuroendocrine differentiationReconstructive surgerySalivary cancerSalivary duct carcinoma

Identifiers

PMID27534564
PMCPMC5429273
OpenAlexW2511889045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.