ArticleJournal of biomedical optics2016
Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 cm in thickness with digital optical phase conjugation.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Optical focusing into scattering media via iterative time reversal guided by absorption nonlinearity.Nature communications · 2025Article
- Size and Illumination Matters: Local Magnetic Actuation and Fluorescence Imaging for Microrobotics.Journal of the Indian Institute of Science · 2024Review
- High-speed single-exposure time-reversed ultrasonically encoded optical focusing against dynamic scattering.Science advances · 2022Article
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
- Reconstruction of Optical Vector-Fields With Applications in Endoscopic Imaging.IEEE transactions on medical imaging · 2019Article
- Implementation of digital optical phase conjugation with embedded calibration and phase rectification.Scientific reports · 2019Article
- High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials.Journal of biomedical optics · 2018Article
- Effects of digital phase-conjugate light intensity on time-reversal imaging through animal tissue.Biomedical optics express · 2018Article
- Time-reversed magnetically controlled perturbation (TRMCP) optical focusing inside scattering media.Scientific reports · 2018Article
- Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses.Journal of biomedical optics · 2018Article
- Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light.Science advances · 2017Article
- High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping.Applied physics letters · 2017Article
- Focusing light inside scattering media with magnetic-particle-guided wavefront shaping.Optica · 2017Article
- Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation.Applied physics letters · 2017Article
- Focusing light through scattering media by transmission matrix inversion.Optics express · 2017Article
- Optical Phase Conjugation with Less Than a Photon per Degree of Freedom.Physical review letters · 2017Article
- Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation.Optica · 2017Article
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Authors and funding
4 authors.
Funding
Abstract
Optical phase conjugation (OPC)-based wavefront shaping techniques focus light through or within scattering media, which is critically important for deep-tissue optical imaging, manipulation, and therapy. However, to date, the sample thickness in OPC experiments has been limited to only a few millimeters. Here, by using a laser with a long coherence length and an optimized digital OPC system that can safely deliver more light power, we focused 532-nm light through tissue-mimicking phantoms up to 9.6 cm thick, as well as through ex vivo chicken breast tissue up to 2.5 cm thick. Our results demonstrate that OPC can be achieved even when photons have experienced on average 1000 scattering events. The demonstrated penetration of nearly 10 cm (∼100 transport mean free paths) has never been achieved before by any optical focusing technique, and it shows the promise of OPC for deep-tissue noninvasive optical imaging, manipulation, and therapy.
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