ArticleJournal of magnetic resonance imaging : JMRI2017
In vivo magnetic resonance elastography to estimate left ventricular stiffness in a myocardial infarction induced porcine model.
Article in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Cardiovascular Magnetic Resonance Elastography: Current Evidence, Challenges, and Future Perspectives.Diagnostics (Basel, Switzerland) · 2026Review
- The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction.Communications biology · 2022Review
- Passive myocardial mechanical properties: meaning, measurement, models.Biophysical reviews · 2021Review
- Shear wave cardiovascular MR elastography using intrinsic cardiac motion for transducer-free non-invasive evaluation of myocardial shear wave velocity.Scientific reports · 2021Article
- Mix and (mis-)match - The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart.Biochimica et biophysica acta. Molecular cell research · 2020Review
- Evaluating Novel Targets of Ischemia Reperfusion Injury in Pig Models.International journal of molecular sciences · 2019Review
- Non-invasive Measurement of Dynamic Myocardial Stiffness Using Acoustic Radiation Force Impulse Imaging.Ultrasound in medicine & biology · 2019Article
- Advances and Future Direction of Magnetic Resonance Elastography.Topics in magnetic resonance imaging : TMRI · 2018Review
- Cardiovascular magnetic resonance elastography: A review.NMR in biomedicine · 2018Review
- Estimation of transversely isotropic material properties from magnetic resonance elastography using the optimised virtual fields method.International journal for numerical methods in biomedical engineering · 2018Article
- Biomechanical assessment of myocardial infarction using optical coherence elastography.Biomedical optics express · 2018Article
- Regional assessment of in vivo myocardial stiffness using 3D magnetic resonance elastography in a porcine model of myocardial infarction.Magnetic resonance in medicine · 2018Article
- Quantification of breast stiffness using MR elastography at 3 Tesla with a soft sternal driver: A reproducibility study.Journal of magnetic resonance imaging : JMRI · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo estimate change in left ventricular (LV) end-systolic and end-diastolic myocardial stiffness (MS) in pigs induced with myocardial infarction (MI) with disease progression using cardiac magnetic resonance elastography (MRE) and to compare it against ex vivo mechanical testing, LV circumferential strain, and magnetic resonance imaging (MRI) relaxometry parameters (T MATERIALS AND
methodsMRI (1.5T) was performed on seven pigs, before surgery (Bx), and 10 (D10), and 21 (D21) days after creating MI. Cardiac MRE-derived MS was measured in infarcted region (MIR) and remote region (RR), and validated against mechanical testing-derived MS obtained postsacrifice on D21. Circumferential strain and MRI relaxometry parameters (T
resultsMean diastolic (D10: 5.09 ± 0.6 kPa; D21: 5.45 ± 0.7 kPa) and systolic (D10: 5.72 ± 0.8 kPa; D21: 6.34 ± 1.0 kPa) MS in MIR were significantly higher (P < 0.01) compared to mean diastolic (D10: 3.97 ± 0.4 kPa; D21: 4.12 ± 0.2 kPa) and systolic (D10: 5.08 ± 0.6 kPa; and D21: 5.16 ± 0.6 kPa) MS in RR. The increase in cardiac MRE-derived MS at D21 (MIR) was consistent and correlated strongly with mechanical testing-derived MS (r(diastolic) = 0.86; r(systolic) = 0.89). Diastolic MS in MIR demonstrated a negative correlation with strain (r = 0.58). Additionally, cardiac MRE-derived MS demonstrated good correlations with post-contrast T
conclusionAs MI progressed, cardiac MRE-derived MS increased in MIR compared to RR, which significantly correlated with mechanical testing-derived MS, T LEVEL OF EVIDENCE: 1 J. Magn. Reson. Imaging 2017;45:1024-1033.
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