Evidence map›Paper›PMID 27532917›Full record

GuidelineJAMA2016

Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement.

US Preventive Services Task Force, Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Karina W Davidson, John W Epling, Francisco A R García, Matthew W Gillman, Alex R Kemper, Alex H Krist and 9 more

Erratum issuedOpen access · bronzeAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in JAMA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 70 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 4 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 176 citations in OpenAlex.

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  20. Algorithms for Treating Dyslipidemia in Youth.Current atherosclerosis reports · 2023
    Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 1 country.

US Preventive Services Task Force
Kirsten Bibbins-DomingoUniversity of California, San Francisco.
David C GrossmanGroup Health Research Institute, Seattle, Washington.
Susan J CurryUniversity of Iowa, Iowa City.
Karina W DavidsonColumbia University, New York, New York.
John W EplingState University of New York Upstate Medical University, Syracuse.
Francisco A R GarcíaPima County Department of Health, Tucson, Arizona.
Matthew W GillmanHarvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Alex R KemperDuke University, Durham, North Carolina.
Alex H KristFairfax Family Practice Residency, Fairfax, Virginia10Virginia Commonwealth University, Richmond.
Ann E KurthYale University, New Haven, Connecticut.
C Seth LandefeldUniversity of Alabama at Birmingham.
Michael LeFevreUniversity of Missouri, Columbia.
Carol M MangioneUniversity of California, Los Angeles.
Douglas K OwensVeterans Affairs Palo Alto Health Care System, Palo Alto, California16Stanford University, Stanford, California.
William R PhillipsUniversity of Washington, Seattle.
Maureen G PhippsBrown University, Providence, Rhode Island.
Michael P PignoneUniversity of Texas at Austin.
Albert L SiuMount Sinai School of Medicine, New York, New York21James J. Peters Veterans Affairs Medical Center, Bronx, New York.
Harvard University · USSUNY Upstate Medical University · USUniversity of Alabama at Birmingham · USUniversity of California, Los Angeles · USUniversity of Iowa · USUniversity of Washington · USBrown University · USDuke University · USIcahn School of Medicine at Mount Sinai · USKaiser Permanente Washington Health Research Institute · USThe University of Texas at Austin · USUniversity of California, San Francisco · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceElevations in levels of total, low-density lipoprotein, and non-high-density lipoprotein cholesterol; lower levels of high-density lipoprotein cholesterol; and, to a lesser extent, elevated triglyceride levels are associated with risk of cardiovascular disease in adults.

objectiveTo update the 2007 US Preventive Services Task Force (USPSTF) recommendation on screening for lipid disorders in children, adolescents, and young adults. EVIDENCE REVIEW: The USPSTF reviewed the evidence on screening for lipid disorders in children and adolescents 20 years or younger--1 review focused on screening for heterozygous familial hypercholesterolemia, and 1 review focused on screening for multifactorial dyslipidemia.

findingsEvidence on the quantitative difference in diagnostic yield between universal and selective screening approaches, the effectiveness and harms of long-term treatment and the harms of screening, and the association between changes in intermediate outcomes and improvements in adult cardiovascular health outcomes are limited. Therefore, the USPSTF concludes that the balance of benefits and harms cannot be determined. CONCLUSIONS AND RECOMMENDATION: The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for lipid disorders in children and adolescents 20 years or younger. (I statement).

Indexed as

Advisory CommitteesPreventive Health ServicesAdolescentAsymptomatic DiseasesCardiovascular DiseasesChildDyslipidemiasHumansHyperlipoproteinemia Type IILipidsMass ScreeningRisk AssessmentUnited StatesYoung AdultLipids

Identifiers

PMID27532917
OpenAlexW2498871569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.