Evidence map›Paper›PMID 27532824›Full record

ArticleJAMA oncology2016

ESR1 Mutations in Cell-Free DNA of Breast Cancer: Predictive "Tip of the Iceberg".

Suzanne A W Fuqua, Yassine Rechoum, Guowei Gu

Abstract readComment
In one paragraph

Article in JAMA oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Combined Assessment of CTC andInternational journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Suzanne A W FuquaLester and Sue Smith Breast Center, Dan L. Duncan Cancer Center, Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Yassine RechoumLester and Sue Smith Breast Center, Dan L. Duncan Cancer Center, Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Guowei GuLester and Sue Smith Breast Center, Dan L. Duncan Cancer Center, Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.

Funding

Replication Stress and DNA Damage Response Drives ESR1 Mutant MetastasisR01CA072038 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI Suzanne AW Fuqua · 1996 to 2026
$6.7M
NCI NIH HHS R01 CA072038
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorBreastBreast NeoplasmsDNADNA MethylationEstrogen Receptor alphaGene Expression Regulation, NeoplasticHumansImmunohistochemistryMutationPrognosisBiomarkers, TumorDNAEstrogen Receptor alpha

Identifiers

PMID27532824
PMCPMC5605796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.