ArticleACS nano2016
Scalable Production of High-Sensitivity, Label-Free DNA Biosensors Based on Back-Gated Graphene Field Effect Transistors.
Article in ACS nano, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Recent Advances in Graphene-Based Field-Effect Transistor Biosensors for Disease Biomarker Detection and Clinical Prospects.Biosensors · 2026Review
- A Suspended Graphene Field-Effect Transistor for Ultra-Sensitive and Label-Free Detection of Cancer Biomarker miR-21.Biosensors · 2026Article
- Future perspectives of GMO detection in agriculture: strategies for electrochemical nucleic acid detection.Mikrochimica acta · 2025Review
- Denaturation methods for reusable magnetic biosensors.Lab on a chip · 2025Article
- Rigid DNA Frameworks Anchored Transistor Enabled Ultrasensitive Detection of Aβ-42 in Serum.Sensors (Basel, Switzerland) · 2025Article
- Advanced Materials for Biological Field-Effect Transistors (Bio-FETs) in Precision Healthcare and Biosensing.Advanced healthcare materials · 2025Review
- High-Precision Micro-Total Analysis of Sodium Ions in Breast Milk.Sensors and actuators. B, Chemical · 2025Article
- Ultrasensitive 3D Stacked Silicon Nanosheet Field-Effect Transistor Biosensor with Overcoming Debye Shielding Effect for Detection of DNA.Biosensors · 2024Article
- Interplay of graphene-DNA interactions: Unveiling sensing potential of graphene materials.Applied physics reviews · 2024Article
- Recent Advances in Field-Effect Transistor-Based Biosensors for Label-Free Detection of SARS-CoV-2.Small science · 2024Article
- Aptamer Renaissance for Neurochemical Biosensing.ACS nano · 2024Review
- Applications of Graphene Field Effect Biosensors for Biological Sensing.Advances in biochemical engineering/biotechnology · 2024Review
- Current and Future Technologies for the Detection of Antibiotic-Resistant Bacteria.Diagnostics (Basel, Switzerland) · 2023Review
- Label-free detection of synthetic, full genomic length HIV-1 RNA at the few-copy level.Sensors and actuators. B, Chemical · 2023Article
- Nanomechanoelectrical approach to highly sensitive and specific label-free DNA detection.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Phase-Coherent Charge Transport through a Porphyrin Nanoribbon.Journal of the American Chemical Society · 2023Article
- Aptamer-functionalized field-effect transistor biosensors for disease diagnosis and environmental monitoring.Exploration (Beijing, China) · 2023Review
- Monitoring CdNanoscale advances · 2023Article
- Graphene-Based Field-Effect Transistors in Biosensing and Neural Interfacing Applications: Recent Advances and Prospects.Analytical chemistry · 2023Review
- Prospects of Biosensors Based on Functionalized and Nanostructured Solitary Materials: Detection of Viral Infections and Other Risks.ACS omega · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very reproducible (>90% yield) fabrication process for label-free DNA biosensors based upon graphene field effect transistors (GFETs) functionalized with single-stranded probe DNA. The shift of the GFET sensor Dirac point voltage varied systematically with the concentration of target DNA. The biosensors demonstrated a broad analytical range and limit of detection of 1 fM for 60-mer DNA oligonucleotide. In control experiments with mismatched DNA oligomers, the impact of the mismatch position on the DNA hybridization strength was confirmed. This class of highly sensitive DNA biosensors offers the prospect of detection of DNA hybridization and sequencing in a rapid, inexpensive, and accurate way.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.