ReviewHuman vaccines & immunotherapeutics2016
A review of immunogenicity and tolerability of live attenuated Hepatitis A vaccine in children.
Review in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of safety and immunogenicity between Healive®, Havrix® and live attenuated Hepatitis A vaccines in pediatric population: a systematic review with meta-analysis.Italian journal of pediatrics · 2025Pooled it
- Immunogenicity persistence of hepatitis A vaccines Healive® and Havrix® among children:15 years follow-up and long-term prediction.Human vaccines & immunotherapeutics · 2023Trial
- Immunogenicity persistence in children of hepatitis A vaccines Healive® and Havrix®: 11 years follow-up and long-term prediction.Human vaccines & immunotherapeutics · 2020Trial
- Five-year antibody persistence in children after one dose of inactivated or live attenuated hepatitis A vaccine.Human vaccines & immunotherapeutics · 2017Trial
- Current Epidemiological Trends and Public Health Challenges of Hepatitis A Virus Infection in Thailand.The American journal of tropical medicine and hygiene · 2025Review
- Identification of mutations in viral proteins involved in cell adaptation using a reverse genetic system of the live attenuated hepatitis A virus vaccine H2 strain.Virologica Sinica · 2024Article
- Cellular immune response to a single dose of live attenuated hepatitis a virus vaccine in obese children and adolescents.Heliyon · 2024Article
- Review
- The infectivity and pathogenicity of hepatitis A virus live-attenuated vaccine strain H2 in type I interferon receptor-deficient mice.Virologica Sinica · 2022Article
- Present and future management of viral hepatitis.World journal of gastroenterology · 2021Review
- Hepatitis A vaccination and its immunological and epidemiological long-term effects - a review of the evidence.Human vaccines & immunotherapeutics · 2021Review
- Impact of Obesity and Being Overweight on the Immunogenicity to Live Attenuated Hepatitis A Vaccine in Children and Young Adults.Vaccines · 2021Article
- Review of long term immunogenicity and tolerability of live hepatitis A vaccine.Human vaccines & immunotherapeutics · 2020Review
- Hepatitis a virus infection in Central-West Tunisia: an age structured model of transmission and vaccination impact.BMC infectious diseases · 2020Article
- Increasing Burden of Hepatitis A in Adolescents and Adults and the Need for Long-Term Protection: A Review from the Indian Subcontinent.Infectious diseases and therapy · 2019Review
- Immunization against Hepatitis A.Cold Spring Harbor perspectives in medicine · 2019Review
- Safety and immunogenicity of VAQTA® in children 12-to-23 months of age with and without administration of other US pediatric vaccines.Human vaccines & immunotherapeutics · 2019Article
- Immunizations in Athletes.Sports healthReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changing epidemiology of Hepatitis A virus (HAV) has led to an increased susceptibility of adolescents and adults to the infection. Vaccination can remarkably reduce the incidence and associated morbidity of HAV infection. This review is focused on the safety and efficacy of H2 strain derived live attenuated Hepatitis A vaccine. We found the vaccine to be highly immunogenic with minimal or negligible safety issues. Moreover, a single dose of live attenuated vaccine persists a long term immune response and can be a preferred option for developing countries. In 2014, Indian Academy of Paediatrics (IAP) also updated their recommendations for H2 vaccine as a single dose as against the previous 2 dose schedule. A focused approach to include the vaccine in national immunization program should be explored.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.