Evidence map›Paper›PMID 27532244›Full record

ReviewCell adhesion & migration2016

Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling.

Aurora Pignata, Hugo Ducuing, Valérie Castellani

Open access · goldAbstract readReview
In one paragraph

Review in Cell adhesion & migration, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Semaphorins in Adult Nervous System Plasticity and Disease.Frontiers in synaptic neuroscience · 2021
    Review
  4. Dorsal commissural axon guidance in the developing spinal cord.Current topics in developmental biology · 2021
    Review
  5. Article
  6. Article
  7. Expression of Genes Involved in Axon Guidance: How Much Have We Learned?International journal of molecular sciences · 2020
    Review
  8. Review
  9. Molecular basis of the functions of the mammalian neuronal growth cone revealed using new methods.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2019
    Review
  10. Spinal RacGAP α-Chimaerin Is Required to Establish the Midline Barrier for Proper Corticospinal Axon Guidance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aurora Pignataa University of Lyon, Université Claude Bernard Lyon 1, NeuroMyogene Institute (INMG), UMR CNRS 5310, INSERM U1217 Lyon , France.
Hugo Ducuinga University of Lyon, Université Claude Bernard Lyon 1, NeuroMyogene Institute (INMG), UMR CNRS 5310, INSERM U1217 Lyon , France.
Valérie Castellania University of Lyon, Université Claude Bernard Lyon 1, NeuroMyogene Institute (INMG), UMR CNRS 5310, INSERM U1217 Lyon , France.
Université Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms governing the navigation of commissural axons during embryonic development have been extensively investigated in the past years, often using the drosophila ventral nerve cord and the spinal cord as model systems. Similarities but also specificities in the general strategies, the molecular signals as well as in the regulatory pathways controlling the response of commissural axons to the guidance cues have been found between species. Whether the semaphorin signaling contributes to midline crossing in the fly nervous system remains unknown, while in contrast, it does play a prominent contribution in vertebrates. In this review we discuss the functions of the semaphorins during commissural axon guidance in the developing spinal cord, focusing on the family member semaphorin 3B (Sema3B) in the context of midline crossing in the spinal cord.

Indexed as

Signal TransductionAnimalsAxonsHumansReceptors, Cell SurfaceSemaphorinsSpinal CordVertebratesReceptors, Cell SurfaceSemaphorinsaxon guidancecommissural neuronsmidlinesemaphorinsspinal cord development

Identifiers

PMID27532244
PMCPMC5160037
OpenAlexW2518614617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.