Evidence map›Paper›PMID 27532106›Full record

ArticlePloS one2016

Qualitative Evaluation of a High-Resolution 3D Multi-Sequence Intracranial Vessel Wall Protocol at 3 Tesla MRI.

Nikki Dieleman, Wenjie Yang, Anja G van der Kolk, Jill Abrigo, Ka Lok Lee, Winnie Chiu Wing Chu, Jaco J M Zwanenburg, Jeroen C W Siero, Ka Sing Wong, Jeroen Hendrikse and 1 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Pooled it
  2. Trial
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  10. Comparison of 3T Intracranial Vessel Wall MRI Sequences.AJNR. American journal of neuroradiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Nikki DielemanDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0003-1841-0924
Wenjie YangDepartment of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Anja G van der KolkDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Jill AbrigoDepartment of Imaging and Interventional Radiology, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Ka Lok LeeDepartment of Imaging and Interventional Radiology, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Winnie Chiu Wing ChuDepartment of Imaging and Interventional Radiology, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Jaco J M ZwanenburgDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Jeroen C W SieroDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Ka Sing WongDepartment of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Jeroen HendrikseDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Fiona Xiang Yan ChenDepartment of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Chinese University of Hong Kong · HKUniversity Medical Center Utrecht · NL

Funding

European Research Council 637024
6 · The paper itself

Abstract

background and purposeIntracranial vessel wall imaging using MRI has great potential as a clinical method for assessing intracranial atherosclerosis. The purpose of the current study was to compare three 3T MRI vessel wall sequences with different contrast weightings (T1w, PD, T2w) and dedicated sagittal orientation perpendicular to the middle cerebral artery, to the reconstructed sagittal image from a transverse 3D T1w volumetric isotropically reconstructed turbo spin-echo acquisition (VIRTA), and provide a clinical recommendation. MATERIALS AND

methodsThe above-mentioned sequences were acquired in 10 consecutive Chinese ischemic stroke or TIA patients (age: 68 years, sex: 4 females) with angiographic-confirmed MCA stenosis at 3T. Institutional review board approval was obtained. Two raters qualitatively scored all images on overall image quality, presence of artifacts, and visibility of plaques. Data were compared using Repeated measures ANOVA and Sidak's adjusted post hoc tests.

resultsAll sequences except the T2w sequence were able to depict the walls of the large vessels of the Circle of Willis (p<0.05). T1w sagittal oblique VIRTA showed significantly more artifacts (p<0.01). Peripherally located plaques were sometimes missed on the sagittal sequences, but could be appreciated on the transverse T1w VIRTA.

conclusionWith the 3T multi-sequence vessel wall protocol we were able to assess the intracranial plaque with two different image contrast weightings. The sequence of preference to include in a clinical protocol would be the transverse 3D T1w VIRTA based on absence of artifacts, larger coverage including the whole Circle of Willis, and excellent lesion depiction.

Indexed as

AgedBrainFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalIntracranial ArteriosclerosisMagnetic Resonance AngiographyMaleMiddle AgedMiddle Cerebral ArteryPlaque, AtheroscleroticProspective Studies

Identifiers

PMID27532106
PMCPMC4988776
OpenAlexW2515617144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.