Evidence map›Paper›PMID 27531929›Full record

ArticleJournal of leukocyte biology2017

SiglecF+Gr1hi eosinophils are a distinct subpopulation within the lungs of allergen-challenged mice.

Caroline M Percopo, Todd A Brenner, Michelle Ma, Laura S Kraemer, Reem M A Hakeem, James J Lee, Helene F Rosenberg

Open access · bronzeAbstract read
In one paragraph

Article in Journal of leukocyte biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Eosinophils and eosinophil-associated diseases: An update.The Journal of allergy and clinical immunology · 2018
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Subsets of Eosinophils in Asthma, a Challenge for Precise Treatment.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Induction of Siglec-FFrontiers in immunology · 2023
    Article
  15. Article
  16. Eosinophils and Lung Cancer: From Bench to Bedside.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Caroline M PercopoInflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Todd A BrennerInflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Michelle MaInflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Laura S KraemerInflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Reem M A HakeemMolecular Signal Transduction Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA; and.
James J LeeMayo Clinic, Scottsdale, Arizona, USA.
Helene F RosenbergInflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA; hrosenberg@niaid.nih.gov.
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USMayo Clinic in Arizona · US

Funding

Eosinophils, Inflammation and ImmunityZIAAI000941 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROSENBERG, HELENE · 2009 to 2020
$8.0M
Biology of the Eosinophilic LeukocyteZ01AI000941 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI ROSENBERG, HELENE · 2004 to 2008
$1.6M
Ribonucleases A in Health and DiseaseZIAAI000942 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROSENBERG, HELENE · 2009 to 2018
$1.5M
Intramural NIH HHS Z01 AI000941
6 · The paper itself

Abstract

Although eosinophils as a group are readily identified by their unique morphology and staining properties, flow cytometry provides an important means for identification of subgroups based on differential expression of distinct surface Ags. Here, we characterize an eosinophil subpopulation defined by high levels of expression of the neutrophil Ag Gr1 (CD45

Indexed as

AllergensAnimalsAntigensAntigens, Differentiation, MyelomonocyticAntigens, LyBone Marrow CellsChemokinesCytoplasmic GranulesEosinophil Major Basic ProteinEosinophil PeroxidaseEosinophilsLungMice, Inbred BALB CMice, Inbred C57BLSialic Acid Binding Immunoglobulin-like LectinsAllergensAntigensAntigens, Differentiation, MyelomonocyticAntigens, LyChemokinesEosinophil Major Basic ProteinEosinophil PeroxidaseLy6G antigen, mouseSialic Acid Binding Immunoglobulin-like LectinsSiglecf protein, mouseallergycytokinesflow cytometryinflammation

Identifiers

PMID27531929
PMCPMC5166438
OpenAlexW2514688858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.