Evidence map›Paper›PMID 27531878›Full record

ArticleOral oncology2016

Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer.

Gypsyamber D'Souza, Yuehan Zhang, Samantha Merritt, Dorothy Gold, Hilary A Robbins, Victoria Buckman, Jennifer Gerber, David W Eisele, Patrick Ha, Joseph Califano and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oral oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  9. Review
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  12. Understanding personal risk of oropharyngeal cancer: risk-groups for oncogenic oral HPV infection and oropharyngeal cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2017
    Article
  13. Article
  14. Dhikr Therapy for Reducing Anxiety in Cancer Patients.Asia-Pacific journal of oncology nursing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Gypsyamber D'SouzaJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615 North Wolfe St, Baltimore, MD 21205, United States.
Yuehan ZhangJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615 North Wolfe St, Baltimore, MD 21205, United States.
Samantha MerrittGreater Baltimore Medical Association, Department of Otolaryngology - Head and Neck Surgery, 6701 North Charles Street, Baltimore, MD 21204, United States.
Dorothy GoldGreater Baltimore Medical Association, Department of Otolaryngology - Head and Neck Surgery, 6701 North Charles Street, Baltimore, MD 21204, United States.
Hilary A RobbinsJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615 North Wolfe St, Baltimore, MD 21205, United States.
Victoria BuckmanJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615 North Wolfe St, Baltimore, MD 21205, United States.
Jennifer GerberJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615 North Wolfe St, Baltimore, MD 21205, United States.
David W EiseleJohns Hopkins University, Department of Otolaryngology - Head and Neck Surgery, 601 North Caroline St, Baltimore, MD 21287, United States.
Patrick HaJohns Hopkins University, Department of Otolaryngology - Head and Neck Surgery, 601 North Caroline St, Baltimore, MD 21287, United States; University of California San Francisco, Department of Otolaryngology - Head and Neck Surgery, 2380 Sutter St, San Francisco, CA 94115, United States.
Joseph CalifanoJohns Hopkins University, Department of Otolaryngology - Head and Neck Surgery, 601 North Caroline St, Baltimore, MD 21287, United States.
Carole FakhryJohns Hopkins University, Department of Otolaryngology - Head and Neck Surgery, 601 North Caroline St, Baltimore, MD 21287, United States. Electronic address: cfakhry@jhmi.edu.
Johns Hopkins University · USGreater Baltimore Medical Center · USUniversity of California, San Francisco · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
TUMOR SUPPRESOR GENE PROMOTER HYPERMETHYLATION FOR DETECTION OF HEAD AND NECKP50DE019032 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI SIDRANSKY, DAVID · 2007 to 2016
$27.1M
NCI NIH HHS P30 CA006973NIDCR NIH HHS P50 DE019032
6 · The paper itself

Abstract

objectivesDiagnosis with an HPV-related oropharyngeal cancer includes unique social issues. However, it is unknown how common these psychosocial issues are for patients and whether they continue after treatment. MATERIALS AND

methodsPatients with pathologically confirmed HPV-positive oropharyngeal cancer (HPV-OPC, n=48) were recruited from two medical centers. Participants completed a computer assisted self interview that explored their psychosocial experiences during and after treatment. We examined responses overall and by age.

resultsThe majority of participants with confirmed HPV-OPC, reported being told that HPV could have (90%) or did cause (77%) their malignancy, but only 52% believed that HPV was the main cause of their OPC. Participants over 65years were less likely than younger participants to report that their doctors told them their tumor was HPV-positive (50% vs 84%, p=0.03). Anxiety that their tumor was HPV-related was a major issue among participants when first diagnosed (93%). However, only 17% still reported anxiety after treatment was complete. While many patients reported that providers discussed the emotional effects of diagnosis and treatment adequately (58%), almost half reported discussing these emotional effects inadequately (24%), or not at all (18%). Further, 18% reported that their families still wondered about some questions that they had never asked.

conclusionAfter treatment, some HPV-OPC patients remain concerned about HPV and have unanswered questions about HPV. Older patients had lower awareness of the role of HPV in their cancer.

Indexed as

AnxietyAgedAlphapapillomavirusFemaleHumansMaleMiddle AgedOropharyngeal NeoplasmsAnxietyHPVOPCPatient experience

Identifiers

PMID27531878
PMCPMC5759043
OpenAlexW2498872103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.