ArticleNature communications2016
Neural correlates of two different types of extinction learning in the amygdala central nucleus.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Reduction in Reward-Driven Behavior Depends on the Basolateral But Not Central Nucleus of the Amygdala in Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Probability and rate of reinforcement in negative prediction error learning.Journal of experimental psychology. Animal learning and cognition · 2025Article
- Alpha-2 agonism in the locus coeruleus impairs learning driven by negative prediction error.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Investigation of the Mozart sonata effect on contextual memory extinction.Einstein (Sao Paulo, Brazil) · 2025Article
- Age-related changes in basal forebrain afferent activation in response to food paired stimuli.Neuroscience letters · 2023Article
- Article
- Engaging endogenous opioid circuits in pain affective processes.Journal of neuroscience research · 2022Review
- Converging vulnerability factors for compulsive food and drug use.Neuropharmacology · 2021Review
- Cross-species studies on orbitofrontal control of inference-based behavior.Behavioral neuroscience · 2021Article
- Effects of Social Isolation on Perineuronal Nets in the Amygdala Following a Reward Omission Task in Female Rats.Molecular neurobiology · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Extinction is a fundamental form of memory updating in which one learns to stop expecting an event that no longer occurs. This learning ensues when one experiences a change in environmental contingencies, that is, when an expected outcome fails to occur (simple extinction), or when a novel inflated expectation of a double outcome (overexpectation) is in conflict with the real outcome, and is a process that has been linked to amygdala function. Here, we show that in rats, the same neuronal population in the amygdala central nucleus updates reward expectancies and behaviour in both types of extinction, and neural changes in one paradigm are reflected in the other. This work may have implications for the management of addiction and anxiety disorders that require treatments based on the outcome omission, and disorders such as obesity that could use overexpectation, but not omission strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.