ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017
The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relationships among impulsive, addictive and sexual tendencies and behaviours: a systematic review of experimental and prospective studies in humans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Pooled it
- Genetic pleiotropy differentially linking brain variation to cannabis use and cannabis use disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Advances in signaling pathway networks involving LHPP in various diseases.Molecular and cellular biochemistry · 2026Review
- Histidine Phosphorylation: Protein Kinases and Phosphatases.International journal of molecular sciences · 2024Review
- The histidine phosphatase LHPP ofFish and shellfish immunology reports · 2023Article
- Polygenic contributions to performance on the Balloon Analogue Risk Task.Molecular psychiatry · 2023Article
- Tumor suppressor LHPP suppresses cell proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma cell lines.Journal of physiology and biochemistry · 2022Article
- Shared genetic basis between reproductive behaviors and anxiety-related disorders.Molecular psychiatry · 2022Article
- m6A methylation mediates LHPP acetylation as a tumour aerobic glycolysis suppressor to improve the prognosis of gastric cancer.Cell death & disease · 2022Article
- LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.Journal of Cancer · 2022Article
- As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma.International journal of biological sciences · 2022Article
- Screening of Pathogenic Missense Single Nucleotide Variants FromBioinformatics and biology insights · 2022Article
- Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.Nature human behaviour · 2021Article
- The many ways that nature has exploited the unusual structural and chemical properties of phosphohistidine for use in proteins.The Biochemical journal · 2021Review
- LHPP exerts a tumor-inhibiting role in glioblastoma via the downregulation of Akt and Wnt/β-catenin signaling.Journal of bioenergetics and biomembranes · 2021Article
- Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality.Translational psychiatry · 2021Article
- LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells.Frontiers in cell and developmental biology · 2021Article
- NME/NM23/NDPK and Histidine Phosphorylation.International journal of molecular sciences · 2020Review
- Article
- Effects of the LHPP gene polymorphism on the functional and structural changes of gray matter in major depressive disorder.Quantitative imaging in medicine and surgery · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
To identify genetic mechanisms involved in the interplay of risky sexual behaviors (RSBs) and alcohol dependence (AD), we conducted genome-wide gene-by-AD (GW-GxAD) analyses of RSB in 3924 alcohol-exposed and sexually experienced subjects. RSBs were defined as a score based on lifetime experiences of unprotected sex and multiple sexual partners. Diagnosis of lifetime AD was defined by DSM-IV criteria. To follow-up the genetic findings, functional magnetic resonance imaging analyses were conducted in an independent sample. A trans-population genome-wide significant signal was identified in LHPP (rs34997829; z=-5.573, p=2.51 × 10
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