Evidence map›Paper›PMID 27531221›Full record

ArticleThe Journal of antibiotics2017

Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus.

Naruhide Miyoshi, Emiko Isogai, Keiichi Hiramatsu, Takashi Sasaki

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Naruhide MiyoshiDepartment of Animal Microbiology, Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan.
Emiko IsogaiDepartment of Animal Microbiology, Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan.
Keiichi HiramatsuDepartment of Microbiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Takashi SasakiDepartment of Microbiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Juntendo University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persulcatusin (IP), which is an antimicrobial peptide found in Ixodes persulcatus midgut, is active against Gram-positive bacteria such as Staphylococcus aureus. Multidrug-resistant bacteria in particular methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA) are a worldwide clinical concern. In the present study, to explore the potential of IP as a new agent against multidrug-resistant S. aureus infections, we evaluated the antimicrobial activity of IP against multidrug-resistant S. aureus strains by MIC

Indexed as

AnimalsAntimicrobial Cationic PeptidesCell MembraneDrug Resistance, Multiple, BacterialIxodesMicrobial Sensitivity TestsMicroscopy, Electron, ScanningPeptidesStaphylococcus aureusAntimicrobial Cationic PeptidesPeptidespersulcatusin

Identifiers

PMID27531221
OpenAlexW2512071144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.