SynthesisDer Nervenarzt2016
Environmental risk factors for autism spectrum disorders.
Synthesis in Der Nervenarzt, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Steroid hormone pathways, vitamin D and autism: a systematic review.Journal of neural transmission (Vienna, Austria : 1996) · 2023Pooled it
- How 25(OH)D Levels during Pregnancy Affect Prevalence of Autism in Children: Systematic Review.Nutrients · 2020Pooled it
- Association Between Age-Specific Sleep Sufficiency and Autism Spectrum Disorder in U.S. Children.Journal of autism and developmental disorders · 2025Article
- The Impact of Seasonality on Mental Health Disorders: A Narrative Review and Extension of the Immunoseasonal Theory.Journal of clinical medicine · 2025Review
- EnvironMental Health: A Framework for an Emerging Field at the Intersection of the Environment and Mental Health Crises.GeoHealth · 2025Review
- Article
- Non-parental caregivers, low maternal education, gastrointestinal problems and high blood lead level: predictors related to the severity of autism spectrum disorder in Northeast China.BMC pediatrics · 2022Article
- Alterations in the autonomic nerve activities of prenatal autism model mice treated with valproic acid at different developmental stages.Scientific reports · 2020Article
- Review
- Association Between 5-HTTLPR Polymorphism and the Risk of Autism: A Meta-Analysis Based on Case-Control Studies.Frontiers in psychiatry · 2019Article
- Binding of mycotoxins to proteins involved in neuronal plasticity: a combined in silico/wet investigation.Scientific reports · 2017Article
- The association between air pollutants and autism spectrum disorders.Environmental science and pollution research international · 2017Review
- Article
- Vitamin D and autism, what's new?Reviews in endocrine & metabolic disorders · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutism spectrum disorders (ASD) are syndromes that are predominantly defined by behavioral features such as impaired social interactions, restricted verbal and nonverbal communication, and repetitive or stereotyped behavior. In the past few decades, the reported prevalence of ASD has increased dramatically. This growth can be partially explained by an increased level of awareness of the problem among professionals and better diagnostic methods. Nevertheless, underpinning causes of ASD have not yet been detailed and explained. It is suggested that rather than having a single causative factor, ASD pathogenesis is influenced by environmental or genetic factors, or a combination of both. The aims of this review are to describe the environmental risk factors associated with ASD so as to provide a reference basis for current and future clinical and experimental work. MATERIALS AND
methodsOn the basis of a PubMed search, we review the existing knowledge on environmental factors associated with ASD.
resultsA series of environmental factors have been repeatedly reported as risk factors for ASD in existing studies.
conclusionAir pollution, organic toxicants, seasonal factors, psychological stress, migration, birth order, and nutrition may have a close relationship with the incidence of ASD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.