ArticleJournal of primary care & community health2017
Association of Decreased High-Density Lipoprotein Cholesterol (HDL-C) With Obesity and Risk Estimates for Decreased HDL-C Attributable to Obesity: Preliminary Findings From a Hospital-Based Study in a City From Northeast India.
Article in Journal of primary care & community health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Trial
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- Burden of premature atherosclerotic cardiovascular disease and its risk factors among young and middle-aged adults in primary care clinics of Karachi, Pakistan.Journal of health, population, and nutrition · 2026Article
- Clinical, biochemical profile and atherosclerotic cardiovascular risk score (ASCVD) in patients with high HDL cholesterol.Irish journal of medical science · 2025Article
- Strong association between atherogenic index of plasma and obesity in college students.BMC endocrine disorders · 2025Article
- Exploring the nonlinear relationship between serum uric acid to high-density lipoprotein cholesterol ratio and obesity in older adults: a cross-sectional study.Frontiers in public health · 2025Article
- The potential of platelet to high-density lipoprotein cholesterol ratio (PHR) as a novel biomarker for heart failure.Scientific reports · 2024Article
- Article
- Evaluation of Body Mass Index, Overweight and Obesity Status, and Cholesterol Levels in Younger Children.JAMA network open · 2023Article
- Anti-Obesity and Anti-Dyslipidemic Effects ofFoods (Basel, Switzerland) · 2023Article
- Article
- Metabolic and inflammatory profiles, gut microbiota and lifestyle factors in overweight and normal weight young thai adults.PloS one · 2023Article
- The Association between Nutritional Status and Length of Hospital Stay among Patients with Hypertension.International journal of environmental research and public health · 2022Article
- Causal relationship of excess body weight on cardiovascular events through risk factors.Scientific reports · 2022Article
- Relationship between nutritional status and length of hospital stay among patients with atrial fibrillation - a result of the nutritional status heart study.Frontiers in nutrition · 2022Article
- Excess Body Mass-A Factor Leading to the Deterioration of COVID-19 and Its Complications-A Narrative Review.Viruses · 2021Review
- Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD.Scientific reports · 2021Article
- Tumor Necrosis Receptor Superfamily Interact with Fusion and Fission of Mitochondria of Adipose Tissue in Obese Patients without Type 2 Diabetes.Biomedicines · 2021Article
- Association of dyslipidemia, hypertension and overweight/obesity with work shift and duration of employment among police officers in a small town in Northeastern Brazil.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is an important risk factor for decrease in high-density lipoprotein cholesterol (HDL-C) levels, which predisposes to cardiovascular diseases. But, the relative contribution of obesity toward decreased HDL-C and the risk estimates of decreased HDL-C attributable to obesity are unavailable. Such measures will help in understanding the extent by which the burden of decreased HDL-C can be reduced by tackling obesity.
objectivesThe objectives of this study were to ( a) determine the association between decreased HDL-C and obesity and ( b) estimate the attributable risk proportion (ARP) and population attributable risk proportion (PARP) for decreased HDL-C due to obesity.
methodsBody mass index (BMI) and waist circumference (WC) were measured as indices of overweight (or generalized obesity) and central obesity, respectively in 190 subjects (95 cases with low HDL-C and 95 healthy controls with normal HDL-C) from Guwahati city. Crude odds ratio (OR) and adjusted OR with 95% confidence interval (CI) were calculated along with the risk estimates (ARP and PARP).
resultsPeople with overweight or generlized obesity (adjusted OR = 4.90, 95% CI = 3.59-6.68), and people with central obesity (adjusted OR = 3.33, 95% CI = 2.39-4.64) had significantly greater odds of developing decreased HDL-C. Among the exposed, 79.8% of the decreased HDL-C cases could be attributed to overweight (or generalized obesity), while 72.8% cases could be attributed to central obesity. In the overall population, the corresponding figures were 57.1% and 36%, respectively.
conclusionDecreased HDL-C is strongly associated with and largely attributable to obesity.
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