Evidence map›Paper›PMID 27531067›Full record

ReviewSchizophrenia research2017

Review of thalamocortical resting-state fMRI studies in schizophrenia.

Monica Giraldo-Chica, Neil D Woodward

Open access · greenAbstract readReview
In one paragraph

Review in Schizophrenia research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 2 syntheses or guidelines pooled it, 230 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Response to Targeted Cognitive Training Correlates with Change in Thalamic Volume in a Randomized Trial for Early Schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Trial
  6. Trial
  7. Multiscale Heterogeneity of White Matter Morphometry in Psychiatric Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Impaired Contour Object Perception in Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Monica Giraldo-ChicaDepartment of Psychiatry & Behavioral Sciences, Vanderbilt University School of Medicine, Nashville, TN, United States.
Neil D WoodwardDepartment of Psychiatry & Behavioral Sciences, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address: neil.woodward@vanderbilt.edu.
Vanderbilt University · US

Funding

Thalamocortical Networks in PsychosisR01MH102266 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WOODWARD, NEIL D. · 2014 to 2018
$2.3M
NIMH NIH HHS R01 MH102266
6 · The paper itself

Abstract

Brain circuitry underlying cognition, emotion, and perception is abnormal in schizophrenia. There is considerable evidence that the neuropathology of schizophrenia includes the thalamus, a key hub of cortical-subcortical circuitry and an important regulator of cortical activity. However, the thalamus is a heterogeneous structure composed of several nuclei with distinct inputs and cortical connections. Limitations of conventional neuroimaging methods and conflicting findings from post-mortem investigations have made it difficult to determine if thalamic pathology in schizophrenia is widespread or limited to specific thalamocortical circuits. Resting-state fMRI has proven invaluable for understanding the large-scale functional organization of the brain and investigating neural circuitry relevant to psychiatric disorders. This article summarizes resting-state fMRI investigations of thalamocortical functional connectivity in schizophrenia. Particular attention is paid to the course, diagnostic specificity, and clinical correlates of thalamocortical network dysfunction.

Indexed as

Magnetic Resonance ImagingAnimalsBrain MappingCerebral CortexHumansNeural PathwaysRestSchizophreniaThalamusCortexResting-state fMRISchizophreniaThalamus

Identifiers

PMID27531067
PMCPMC5297399
OpenAlexW2507392736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.