Evidence map›Paper›PMID 27531014›Full record

ArticleBMC urology2016

Physical activity before radical prostatectomy reduces sick leave after surgery - results from a prospective, non-randomized controlled clinical trial (LAPPRO).

E Angenete, U Angerås, M Börjesson, J Ekelund, M Gellerstedt, T Thorsteinsdottir, G Steineck, E Haglind

Registry-linked trialOpen access · goldAbstract readComparative StudyControlled Clinical TrialMulticenter Study
In one paragraph

Article in BMC urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05576766 (Impact of Enhanced Recovery After Surgery), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05576766 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Enhanced Recovery After Surgery (ERAS) Pathway on Outcomes in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy: A Randomized Controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2025 to 2026Enrolled54ConditionsProstate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, PrehabilitationArmsRoutine care, ERAS management pathway
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Work after prostate cancer: a systematic review.Journal of cancer survivorship : research and practice · 2019
    Pooled it
  4. Article
  5. Review
  6. Urinary dysfunction in patients with rectal cancer: a prospective cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020
    Observational
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

E AngeneteDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden. eva.angenete@vgregion.se.
U AngeråsDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden.
M BörjessonSwedish School of Sport and Health Sciences, Stockholm, Sweden.
J EkelundDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden.
M GellerstedtUniversity West, Trollhättan, Sweden.
T ThorsteinsdottirFaculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
G SteineckDivision of Clinical Cancer Epidemiology, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
E HaglindDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, SSORG, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden.
Sahlgrenska University Hospital · SEKarolinska Institutet · SEKarolinska University Hospital · SEUniversity of Iceland · ISUniversity West · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have reported that early physical rehabilitation after surgical procedures is associated with improved outcome measured as shorter hospital stay and enhanced recovery. The aim of this study was to explore the relationship between the preoperative physical activity level and subsequent postoperative complications, sick-leave and hospital stay after radical prostatectomy for prostate cancer in the setting of the LAPPRO trial (LAParoscopic Prostatectomy Robot Open).

methodsLAPPRO is a prospective controlled trial, comparing robot-assisted laparoscopic and open surgery for localized prostate cancer between 2008 and 2011. 1569 patients aged 64 or less with an occupation were included in this sub-study. The Gleason score was <7 in 52 % of the patients. Demographics and the level of self-assessed preoperative physical activity, length of hospital stay, complications, quality of life, recovery and sick-leave were extracted from clinical record forms and questionnaires. Multivariable logistic regression, with log-link and logit-link functions, was used to adjust for potential confounding variables.

resultsThe patients were divided into four groups based on their level of activity. As the group with lowest engagement of physical activity was found to be significantly different in base line characteristics from the other groups they were excluded from further analysis. Among patients that were physically active preoperativelly (n = 1467) there was no significant difference between the physical activity-groups regarding hospital stay, recovery or complications. However, in the group with the highest self-assessed level of physical activity, 5-7 times per week, 13 % required no sick leave, compared to 6.3 % in the group with a physical activity level of 1-2 times per week only (p < 0.0001).

conclusionsIn our study of med operated with radical prostatectomy, a high level of physical activity preoperatively was associated with reduced need for sick leave after radical prostatectomy compared to men with lower physical activity.

trial registrationThe trial is registered at the ISCRTN register. ISRCTN06393679 .

Indexed as

ExerciseAdultHumansLength of StayMaleMiddle AgedProspective StudiesProstatectomyProstatic NeoplasmsSick LeavePhysical fitnessProstatectomyProstatic neoplasm

Identifiers

PMID27531014
PMCPMC4986175
OpenAlexW2515934225

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.