Evidence map›Paper›PMID 27530961›Full record

Trial reportPsycho-oncology2017

Effects of a multicomponent physical activity behavior change intervention on fatigue, anxiety, and depressive symptomatology in breast cancer survivors: randomized trial.

Laura Q Rogers, Kerry S Courneya, Philip M Anton, Steven Verhulst, Sandra K Vicari, Randall S Robbs, Edward McAuley

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03760653 (Physical Activity Along With a Probiotic for the Immune System and Quality of Life Improvement in Breast Cancer Survivor), which is not on this map. Cited by 53 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03760653 nawithdrawnnot on this mapstarted 2018, after this paper: background citation

Physical Activity Along With a Probiotic for the Immune System and Quality of Life Improvement in Breast Cancer Survivor: A Randomised Controlled Pilot Study

TypeinterventionalSponsorUniversidad Europea de MadridRan2018 to 2019Enrolled0ConditionsBreast Cancer FemalesArmsPhysical Exercise and probiotic group, Probiotic group, Placebo group
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cardiovascular training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Pooled it
  4. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Distress Management, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2019
    Guideline
  10. Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Ease of walking associates with greater free-living physical activity and reduced depressive symptomology in breast cancer survivors: pilot randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Trial
  17. Trial
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura Q RogersDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Kerry S CourneyaFaculty of Physical Education and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Philip M AntonDepartment of Kinesiology, Southern Illinois University Carbondale, Carbondale, IL, USA.
Steven VerhulstStatistics and Research Informatics Core, Center for Clinical Research, Southern Illinois University School of Medicine, Springfield, IL, USA.
Sandra K VicariDepartment of Psychiatry, Southern Illinois University School of Medicine, Springfield, IL, USA.
Randall S RobbsStatistics and Research Informatics Core, Center for Clinical Research, Southern Illinois University School of Medicine, Springfield, IL, USA.
Edward McAuleyDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
Enhancing physical activity after breast cancer diagnosis: randomized trialR01CA136859 · NCI · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI ROGERS, LAURA Q · 2009 to 2012
$2.6M
Enhancing physical activity after breast cancer diagnosis: randomized trialU01CA136859 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, LAURA Q · 2012 to 2015
$2.0M
NCI NIH HHS R01 CA136859NCI NIH HHS U01 CA136859NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

objectivesTo determine the effects of the 3-month multicomponent Better Exercise Adherence after Treatment for Cancer (BEAT Cancer) physical activity behavior change intervention on fatigue, depressive symptomatology, and anxiety.

methodsPostprimary treatment breast cancer survivors (n = 222) were randomized to BEAT Cancer or usual care. Fatigue Symptom Inventory and Hospital Anxiety and Depression Scale were assessed at baseline, postintervention (month 3; M3), and follow-up (month 6; M6).

resultsAdjusted linear mixed-model analyses demonstrated significant effects of BEAT Cancer vs usual care on fatigue intensity (M3 mean between group difference [M] = -0.6; 95% confidence interval [CI] = -1.0 to -0.2; effect size [d] = -0.32; P = .004), fatigue interference (M3 M = -0.8; CI = -1.3 to -0.4; d = -0.40; P < .001), depressive symptomatology (M3 M = -1.3; CI = -2.0 to -0.6; d = -0.38; P < .001), and anxiety (M3 M = -1.3; CI = -2.0 to -0.5; d = -0.33; P < .001). BEAT Cancer effects remained significant at M6 for all outcomes (all P values <.05; d = -0.21 to -.35). Clinically meaningful effects were noted for fatigue intensity, fatigue interference, and depressive symptomatology.

conclusionsBEAT Cancer reduces fatigue, depressive symptomatology, and anxiety up to 3 months postintervention in postprimary treatment breast cancer survivors. Further study is needed to determine sustainable methods for disseminating and implementing the beneficial intervention components.

Indexed as

Exercise TherapyMotor ActivityAnxietyAnxiety DisordersBreast NeoplasmsCancer SurvivorsExerciseFatigueFemaleHumansMiddle AgedQuality of LifeTreatment Outcomecancerexerciseoncologypsychosocialsurvivorship

Identifiers

PMID27530961
PMCPMC5511085

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.