Evidence map›Paper›PMID 27529274›Full record

Trial reportNutrients2016

Improvement of Triglyceride Levels through the Intake of Enriched-β-Conglycinin Soybean (Nanahomare) Revealed in a Randomized, Double-Blind, Placebo-Controlled Study.

Mie Nishimura, Tatsuya Ohkawara, Yuji Sato, Hiroki Satoh, Yoko Takahashi, Makita Hajika, Jun Nishihira

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Soybean genetic resources contributing to sustainable protein production.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Review
  4. Mung Bean (Nutrients · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mie NishimuraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan. mnishimura@do-johodai.ac.jp.
Tatsuya OhkawaraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan. tatuyao@mail.goo.ne.jp.
Yuji SatoDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan. ysato@do-johodai.ac.jp.
Hiroki SatohDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan. h-satoh@do-johodai.ac.jp.
Yoko TakahashiDivision of Food Function Research, Food Research Institute, NARO, Tsukuba, Ibaraki 305-8642, Japan. youkot@affrc.go.jp.
Makita HajikaInstitute of Crop Science, NARO, Tsukuba, Ibaraki 305-8518, Japan. mhajika@affrc.go.jp.
Jun NishihiraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu, Hokkaido 069-8585, Japan. nishihira@do-johodai.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soybean is recognized as a beneficial food with various functional components, such as β-conglycinin, which improves lipid metabolism. We evaluated the effects of the β-conglycinin-rich soybean Nanahomare on triglyceride (TG) levels. In this randomized, double-blind, placebo-controlled study, we divided 134 adult subjects into test and placebo groups that consumed processed food containing enriched-β-conglycinin soybean or low-β-conglycinin soybean. Hematological tests and body composition measurements were performed at weeks 0 (baseline), 4, 8, and 12 of the study period. TG levels significantly decreased in the test group compared with the placebo group at weeks 4 (change from baseline to week 4, placebo: 0.27 ± 44.13 mg/dL, test: -20.31 ± 43.74 mg/dL, p = 0.035) and 12 (change from baseline to week 12, placebo: -0.14 ± 65.83 mg/dL, test: -21.30 ± 46.21 mg/dL, p = 0.041). In addition, among subjects whose baseline TG levels were ≥100 mg/dL, the levels significantly improved in the test group at weeks 4 (p = 0.010) and 12 (p = 0.030), whereas the levels were not different between the test and placebo groups among those whose baseline levels were <100 mg/dL. These results suggest that the ingestion of enriched-β-conglycinin soybean improves serum TG levels.

Indexed as

Food, FortifiedAdultAgedAntigens, PlantBody CompositionDouble-Blind MethodEatingFemaleGlobulinsGlycine maxHumansMaleMiddle AgedSeed Storage ProteinsSoybean ProteinsTime FactorsAntigens, Plantbeta-conglycinin protein, Glycine maxGlobulinsSeed Storage ProteinsSoybean ProteinsTriglyceridesclinical trialNanahomaresoybeantriglycerideβ-conglycinin

Identifiers

PMID27529274
PMCPMC4997404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.