Evidence map›Paper›PMID 27529228›Full record

ReviewInternational journal of molecular sciences2016

Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses.

Dragos Cretoiu, Jiahong Xu, Junjie Xiao, Sanda M Cretoiu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Review
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  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dragos CretoiuDivision of Cellular and Molecular Biology and Histology, Department of Morphological Sciences, Carol Davila University of Medicine and Pharmacy, Bucharest 050474, Romania. dragos@cretoiu.ro.
Jiahong XuDepartment of Cardiology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China. jhx_tj@hotmail.com.
Junjie XiaoCardiac Regeneration and Ageing Lab, Experimental Center of Life Sciences, School of Life Science, Shanghai University, Shanghai 200444, China. junjiexiao@live.cn.
Sanda M CretoiuDivision of Cellular and Molecular Biology and Histology, Department of Morphological Sciences, Carol Davila University of Medicine and Pharmacy, Bucharest 050474, Romania. sanda@cretoiu.ro.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Entering the new millennium, nobody believed that there was the possibility of discovering a new cellular type. Nevertheless, telocytes (TCs) were described as a novel kind of interstitial cell. Ubiquitously distributed in the extracellular matrix of any tissue, TCs are regarded as cells with telopodes involved in intercellular communication by direct homo- and heterocellular junctions or by extracellular vesicle (EVs) release. Their discovery has aroused the interest of many research groups worldwide, and many researchers regard them as potentially regenerative cells. Given the experience of our laboratory, where these cells were first described, we review the evidence supporting the fact that TCs release EVs, and discuss alternative hypotheses about their future implications.

Indexed as

AnimalsExosomesExtracellular VesiclesHumansMicroscopy, Electron, TransmissionTelocytesectosomesexosomesextracellular vesiclestelocytestelopodes

Identifiers

PMID27529228
PMCPMC5000719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.